30516-21-3

Basic information

• Product Name: 1-(1H-benzo[d][1,2,3]triazol-1-yl)-2-phenylethan-1-one
• Synonyms: 1-(1H-benzo[d][1,2,3]triazol-1-yl)-2-phenylethan-1-one
• CAS NO: 30516-21-3
• Molecular Weight: 237.261
• Mol File: 30516-21-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1-(1H-benzo[d][1,2,3]triazol-1-yl)-2-phenylethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1H-benzo[d][1,2,3]triazol-1-yl)-2-phenylethan-1-one(30516-21-3)
• EPA Substance Registry System: 1-(1H-benzo[d][1,2,3]triazol-1-yl)-2-phenylethan-1-one(30516-21-3)

Safety Data

• Hazardous Substances Data: 30516-21-3(Hazardous Substances Data)

Upstream product

• 95-14-7 1,2,3-Benzotriazole 
• 103-80-0 phenylacetyl chloride 
• 103-82-2 phenylacetic acid 
• 4231-62-3 1-benzoyl-1H-benzotriazole 
• 37073-15-7 1-(methanesulfonyl)-1H-1,2,3-benzotriazole 

Downstream Products

• 3389-53-5 phenylacetylpyrrolidine 
• 13196-28-6 2-phenyl-1-(thiophen-2-yl)ethan-1-one 
• 138350-43-3 2-phenyl-1-(5-methyl-2-furyl)-1-ethanone 
• 7500-45-0 N-benzylphenylacetamide 
• 60-12-8 2-phenylethanol 
• 681455-21-0 N-[1-(benzotriazol-1-yl)-2-phenylethylidene]-4-methylaniline 
• 1069051-39-3 1-(5-bromo-1H-indol-3-yl)-2-phenylethanone 
• 1043910-92-4 C₅₃H₆₃N₅O₇ 
• 1043910-21-9 3-demethoxycarbonyl-3-(phenylacetylamino)methylvindoline 
• 33054-04-5 phenylacetyl azide 
• 883-39-6 1-phenyl-1H-benzotriazole 
• 2621-78-5 ethyl N-benzylcarbamate 
• 6468-48-0 6-Methoxy-3-phenyl-coumarin 
• 955-10-2 3-phenylcumarin 

Relevant articles and documents

Synthesis and structure-activity relationship studies of cytotoxic anhydrovinblastine amide derivatives

A series of 3-demethoxycarbonyl-3-amide methyl anhydrovinblastine derivatives (5b-24b) was designed, synthesized, and evaluated for their proliferation inhibition activities against two tumor cell lines (A549 and HeLa). Most of the amide anhydrovinblastin

Exploiting the Imidazolium Effect in Base-free Ammonium Enolate Generation: Synthetic and Mechanistic Studies

N-Acyl imidazoles and catalytic isothiourea hydrochloride salts function as ammonium enolate precursors in the absence of base. Enantioselective Michael addition–cyclization reactions using different α,β-unsaturated Michael acceptors have been performed to form dihydropyranones and dihydropyridinones with high stereoselectivity. Detailed mechanistic studies using RPKA have revealed the importance of the “imidazolium” effect in ammonium enolate formation and have highlighted key differences with traditional base-mediated processes.

C-acylation of 2-methylfuran and thiophene using N-acylbenzotriazoles

Reactions of 2-methylfuran and thiophene with readily available N-acylbenzotriazoles (RCOBt, where R = 4-tolyl, 4-methoxyphenyl, benzyl, 4-nitrophenyl, 4-diethylaminophenyl, 2-pyridyl and 1-naphthyl) in the presence of TiCl4 or ZnBr2 produced 2-methyl-4-acylfurans 2a-e and 2-acylthiophenes 3a-f in average yields of 54 % and 75 %, respectively. Literature yields for the preparation of the same compounds are significantly lower.