30530-44-0

Usage

Uses

Used in Pharmaceutical Industry:
2,4-DIAMINO-6-(4-FLUOROPHENYL)-1,3,5-TRIAZINE is used as a key intermediate in the synthesis of pharmaceuticals for its ability to form a variety of biologically active compounds. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2,4-DIAMINO-6-(4-FLUOROPHENYL)-1,3,5-TRIAZINE serves as a building block in the creation of agrochemicals, such as herbicides and pesticides. Its reactivity enables the production of effective compounds that protect crops from pests and diseases.
Used as an Antiviral Agent:
2,4-DIAMINO-6-(4-FLUOROPHENYL)-1,3,5-TRIAZINE has been studied for its potential as an antiviral agent, demonstrating activity against various viral infections. Its unique chemical structure allows for the development of compounds that can inhibit viral replication and reduce the severity of viral diseases.
Used as an Anticancer Agent:
Research has also explored the use of 2,4-DIAMINO-6-(4-FLUOROPHENYL)-1,3,5-TRIAZINE as an anticancer agent. Its potential to interfere with cancer cell growth and proliferation makes it a promising candidate for the development of novel anticancer drugs.
Used in Organic Synthesis:
Beyond its applications in pharmaceuticals and agrochemicals, 2,4-DIAMINO-6-(4-FLUOROPHENYL)-1,3,5-TRIAZINE is also utilized as a versatile building block in the synthesis of various organic compounds. Its reactivity allows for the creation of a wide range of molecules with diverse applications in different industries.

InChI:InChI=1/C9H8FN5/c10-6-3-1-5(2-4-6)7-13-8(11)15-9(12)14-7/h1-4H,(H4,11,12,13,14,15)

Upstream product

• 1194-02-1 4-fluorobenzonitrile 
• 1115-70-4 metformin hydrochloride 
• 127099-85-8 N-Cyanoguanidine 
• 3397-62-4 2-Chloro-4,6-diamino-1,3,5-triazine 
• 1765-93-1 4-fluoroboronic acid 

Relevant academic research and scientific papers

2,4,6-trisubstituted-1,3,5-s-triazine compound and preparation and application thereof

The invention provides a 2,4,6-trisubstituted-1,3,5-s-triazine compound as well as preparation and application thereof, and biguanide or dimethyl biguanide hydrochloride is used as an initial raw material to react with a cyano compound under an alkaline condition to prepare the 2,4,6-trisubstituted-1,3,5-s-triazine compound. The invention provides a simple and convenient synthetic method of a 2,4,6-trisubstituted-1,3,5-s-triazine compound, and the compound provided by the invention can be applied to preparation of an anti-myelogenous leukemia medicine, namely an enasidenib medicine. Compared with the prior art, the method for preparing the enasidenib has the advantages that two-step reaction is reduced, the use of a halogenating reagent is avoided, and the method is a green and environment-friendly chemical process. The structural formula I is shown in the specification.

Microwave-assisted clean synthesis of 6-aryl-2,4-diamino-1,3,5-triazines in [bmim][PF6]

An efficient and green approach was developed to prepare 6-aryl-2,4-diamino-1,3,5-triazines from corresponding arylnitriles and dicyanodiamide in ionic liquid [bmim][PF6] under computer-controlled microwave irradiation. Particularly valuable features of this method included the short reaction time, good yield, convenient operation and eco-friendly solvent.

Synthesis of 6-aryl-2,4-diamino-pyrimidines and triazines using palladium catalysed Suzuki cross-coupling reactions

The high yielding synthesis of 6-aryl-2,4-diaminopyrimidines and triazines via palladium catalysed Suzuki cross-coupling reactions of commercially available 6-chloro-2,4-diaminopyrimidine 1 or 6-chloro-2,4-diaminotriazine 8 and aryl boronic acids are desc

ANTICANCER COMPOSITION AND COMPOUND

An anticancer composition containing a compound represented by general formula (I) or a pharmacologically acceptable acid addition salt thereof. In formula (I), R10 and R20 may be the same or different from each other and each represents hydrogen, halogen, amino, aralkylamino, nitro, lower alkyl, lower alkoxy, lower alkoxyalkoxy, lower aralkyloxy or acyl; R30 and R40 may be the same or different from each other and each represents hydrogen, nicotinoyl, benzoyl or lower alkoxy; and n represents 0 or 1.