305448-92-4

Usage

Uses

Used in Organic Synthesis:
3-Methanesulfonylaminophenylboronic acid, pinacol ester is used as a building block for the synthesis of biologically active molecules, pharmaceuticals, and agrochemicals. Its presence in Suzuki-Miyaura cross-coupling reactions allows for the formation of carbon-carbon and carbon-heteroatom bonds, which are crucial for creating complex organic structures.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Methanesulfonylaminophenylboronic acid, pinacol ester is used as a key intermediate in the development of new drugs. Its ability to form stable bonds with other molecules makes it a valuable component in the synthesis of potential therapeutic agents.
Used in Agrochemical Industry:
3-Methanesulfonylaminophenylboronic acid, pinacol ester is also employed in the agrochemical industry for the synthesis of various agrochemicals. Its role in creating stable and effective compounds contributes to the development of new pesticides and other agricultural products.
Used in Research and Development:
In the field of research and development, 3-Methanesulfonylaminophenylboronic acid, pinacol ester is used as a versatile tool for exploring new chemical reactions and bond formations. Its unique properties make it an essential component in the advancement of organic chemistry and the discovery of novel compounds.

InChI:InChI=1/C13H20BNO4S/c1-12(2)13(3,4)19-14(18-12)10-7-6-8-11(9-10)15-20(5,16)17/h6-9,15H,1-5H3

Upstream product

• 54769-22-1 1-methanesulfonyloxy-1,2,3-benzotriazole 
• 210907-84-9 3-aminophenylboronic acid pinacolate 
• 83922-51-4 3-(methylsulfonyl)amino-1-bromo-benzene 
• 73183-34-3 bis(pinacol)diborane 
• 206658-89-1 3-aminobenzeneboronic acid monohydrate 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 591-19-5 m-Bromoaniline 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 1605326-59-7 (S)-N-(3-(4-amino-6-((1-(5-methyl-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl)amino)pyrimidin-5-yl)phenyl)methanesulfonamide 
• 1425042-35-8 C₂₅H₁₉N₇O₂ 
• 1425042-62-1 C₂₄H₁₉N₇O 
• 1425042-63-2 C₂₂H₁₈N₆O 
• 1064680-88-1 N-{3-[2-hydroxy-6-(3-hydroxyphenyl)-1-naphthyl]phenyl}-methanesulfonamide 
• 1227089-92-0 N-(3-(6-(1H-indazol-4-yl)-1-methyl-1H-pyrazolo[3,4-b]pyridin-4-yl)phenyl)methanesulfonamide 
• 1013641-63-8 C₂₃H₂₃N₃O₆S 
• 1073538-33-6 N-{3-[2-(cyclohexylmethyIene-amino)-7-methyl-1-oxo-2,3-dihydro-1H-isoindol-5-yl]-phenyI}-methanesulfonamide 

Relevant academic research and scientific papers

BTK Inhibitors and uses thereof

The invention discloses a bruton's tyrosine kinase (BTK) inhibitor and use thereof. Specifically, the invention provides heteroaromatic compounds or stereoisomers, geometrical isomers, tautomers, racemates, nitrogen oxides, hydrates, solvates, metabolites and pharmaceutically acceptable salts or prodrugs thereof, and pharmaceutical compositions containing the heteroaromatic compounds; the invention also discloses use of the heteroaromatic compounds or the pharmaceutical compositions containing the heteroaromatic compounds in preparation of medicines; the medicines can be used for treating autoimmune diseases, inflammatory diseases or proliferative diseases.

3-(PYRAZOLYL)-1H-PYRROLO[2,3-b]PYRIDINE DERIVATIVES AS KINASE INHIBITORS

The present application relates to novel 3-(pyrazolyl)-lH-pyrrolo[2,3-b]pyridine derivatives of formula (I), as protein kinase inhibitors. The invention particularly relates to compounds of formula (I), preparation of compounds and pharmaceutical compositions thereof. The invention further relates to pharmaceutically acceptable salts and compositions comprising the said novel 3-(pyrazolyl)-lH-pyrrolo[2,3-b]pyridine derivatives and their use in the treatment of various disorders.

NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES

The present invention provides PI3K protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorders with them.

NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES

The present invention provides PI3K protein kinase modulators, methods of preparing them, pharmaceutical compositions containing them and methods of treatment, prevention and/or amelioration of kinase mediated diseases or disorders with them.

2-Amino-aryl-7-aryl-benzoxazoles as potent, selective and orally available JAK2 inhibitors

A series of novel benzoxazole derivatives has been designed and shown to exhibit attractive JAK2 inhibitory profiles in biochemical and cellular assays, capable of delivering compounds with favorable PK properties in rats. Synthesis and structure-activity relationship data are also provided.

Preparation of Aminoaryl and Aminoheteroaryl Boronic Acids and Derivatives Thereof

The invention relates to a method for preparation of aminoaryl- or aminoheteroarylboronic acids and esters and salts thereof in which an optionally substituted aminoaryl or aminoheteroaryl compound is protected at its nitrogen site via condensation with a carbonyl compound, subsequently metalated and converted with a suitable boron compound. Depending on the subsequent work-up and removal of the protective group, the corresponding boronic acid, the anhydride or the boronic acid ester thereof is obtained

Sulfonamide derivatives

The present invention provides certain sulfonamide derivatives useful for potentiating glutamate receptor function in a patient and therefore, useful for treating a wide variety of conditions, such as psychiatric and neurological disorders.