3055-46-7Relevant academic research and scientific papers
Design, physico-chemical characterization andin vitrobiological activity of organogold(iii) glycoconjugates
Pettenuzzo, Andrea,Vezzù, Keti,Di Paolo, Maria Luisa,Fotopoulou, Eirini,Marchiò, Luciano,Via, Lisa Dalla,Ronconi, Luca
supporting information, p. 8963 - 8979 (2021/07/02)
To develop new metal-based glycoconjugates as potential anticancer agents, four organometallic gold(iii)-dithiocarbamato glycoconjugates of the type [AuIII(2-Bnpy)(SSC-Inp-GlcN)](PF6) (2-Bnpy: 2-benzylpyridine; Inp: isonipecotic moie
Synthetic development of sugar amino acid oligomers towards novel podophyllotoxin analogues
Bouchard, Megan,Tremblay, Thomas,Paré-Lacroix, Marie-Pier,Gagné-Boulet, Mathieu,Fortin, Sébastien,Giguère, Denis
, (2021/11/30)
In this work, we have developed an approach for the synthesis of sugar amino acid oligomers based on the glucosamine scaffold. We found that the solid-phase approach was unsuccessful for the preparation of sugar amino acid oligomers and the limitation of
Ultrasonication-Assisted Synthesis of a d-Glucosamine-Based β-CD Inclusion Complex and Its Application as an Aqueous Heterogeneous Organocatalytic System
Rani, Dhiraj,Sethi, Aaftaab,Kaur, Khushwinder,Agarwal, Jyoti
, p. 9548 - 9557 (2020/09/09)
For the first time, an inclusion complex has been crafted between a carbohydrate-based molecule and a β-cyclodextrin (CD) hydrophobic cavity for asymmetric catalytic applications. This novel d-glucosamine-based inclusion compound has been synthesized in h
Ring-Opening Reactions of the N-4-Nosyl Hough-Richardson Aziridine with Nitrogen Nucleophiles
Ru?il, Tomá?,Trávní?ek, Zdeněk,Canka?, Petr
, p. 723 - 730 (2017/04/26)
Dinosylated α-d-glucopyranoside was directly transformed into α-d-altropyranosides via in situ formed N-4-nosyl Hough-Richardson aziridine with nitrogen nucleophiles under mild conditions in fair to excellent yields. The scope of the aziridine ring-opening reaction was substantially broadened contrary to the conventional methods introducing solely the azide anion at high temperatures. If necessary, the N-4-nosyl Hough-Richardson aziridine can be isolated by filtration in a very good yield and high purity.
N-acetylgalactosamine green synthetic method
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Paragraph 0037; 0038, (2016/11/28)
The present invention discloses a N-acetylgalactosamine green synthetic method. According to the method, N-acetylglucosamine as a raw material is successively condensed with an alcohol and pivaloyl chloride, and then N-acetylgalactosamine can be obtained
Sugar derived alkamine catalytic imine reduction method
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Paragraph 0035; 0036; 0037, (2016/10/07)
The invention discloses a method used for catalytic reduction of imine with saccharide-derivatized amino alcohol. According to the method, imine is taken as a substrate. The method comprises following steps: 1) imine and saccharide-derivatized amino alcohol are dissolved in an organic solvent I, wherein molar ratio of imine to saccharide-derivatized amino alcohol ranges from 100:1-20; 2) trichlorosilane with 1.5 to 5 times equivalent weights is added into a solution obtained via step 1) dropwise, an obtained mixture is stirred and reacted for 12 to 36h at a temperature of -20 to 40 DEG C, and a saturated sodium bicarbonate solution is used for quenching; 3) a material obtained via step 2) is extracted with an organic solvent II, and is subjected to column chromatography isolation so as to obtain amine compounds.
Synthetic heparin pentasaccharides
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Page/Page column 36; 37, (2016/02/12)
Preparation and use of synthetic monosaccharides, disaccharides, trisaccharides, tetrasaccharides and pentasaccharides useful for the preparation of synthetic heparinoids.
Glucosamine-based primary amines as organocatalysts for the asymmetric aldol reaction
Agarwal, Jyoti,Peddinti, Rama Krishna
scheme or table, p. 3502 - 3505 (2011/06/21)
Glucosamine derivatives have been synthesized starting from commercially available N-acetyl-D-glucosamine/glucosamine hydrochloride and have been employed successfully as efficient organocatalysts for the direct asymmetric aldol reaction between cyclohexa
Oligo-Aminosaccharide compound
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Page/Page column 8, (2011/01/12)
An oligo-aminosaccharide compound formed by binding 3 to 6 saccharides, such as 2,6-diamino-2,6-dideoxy-α-(1→4)-D-glucopyranose oligomers, or a salt thereof, which has high affinity to a double-stranded nucleic acid.
Synthesis and characterization of d-glucosamine-derived low molecular weight gelators
Goyal, Navneet,Cheuk, Sherwin,Wang, Guijun
supporting information; experimental part, p. 5962 - 5971 (2010/09/18)
Carbohydrate-based low molecular weight gelators are an interesting class of molecules with many potential applications. Previously, we have found that certain esters and carbamates of 4,6-O-benzylidene-α-d-methyl- glucopyranoside are low molecular weight
