306934-99-6

Basic information

• Product Name: ETHYL 2-AMINO-4-(4-BROMOPHENYL)-3-THIOPHENECARBOXYLATE
• Synonyms: ETHYL 2-AMINO-4-(4-BROMOPHENYL)THIOPHENE-3-CARBOXYLATE;ETHYL 2-AMINO-4-(4-BROMOPHENYL)-3-THIOPHENECARBOXYLATE;AKOS MSC-0438;AKOS B000791;2-AMINO-4-(4-BROMO-PHENYL)-THIOPHENE-3-CARBOXYLIC ACID ETHYL ESTER;TIMTEC-BB SBB005954;Ethyl 2-amino-4-(4-bromophenyl)-3-thiophenecarboxylate ,98%;2-Amino-4-(4-bromophenyl)-3-(ethoxycarbonyl)thiophene
• CAS NO: 306934-99-6
• Molecular Formula: C₁₃H₁₂BrNO₂S
• Molecular Weight: 326.21
• Mol File: 306934-99-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 121-125°C
• Boiling Point: 433.7 °C at 760 mmHg
• Flash Point: 216.1 °C
• Appearance: /
• Density: 1.502±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 1E-07mmHg at 25°C
• Refractive Index: 1.633
• PKA: -0.23±0.10(Predicted)
• CAS DataBase Reference: ETHYL 2-AMINO-4-(4-BROMOPHENYL)-3-THIOPHENECARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-AMINO-4-(4-BROMOPHENYL)-3-THIOPHENECARBOXYLATE(306934-99-6)
• EPA Substance Registry System: ETHYL 2-AMINO-4-(4-BROMOPHENYL)-3-THIOPHENECARBOXYLATE(306934-99-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 306934-99-6(Hazardous Substances Data)

Usage

Chemical Properties

Light yellow solid

InChI:InChI=1/C13H12BrNO2S/c1-2-17-13(16)11-10(7-18-12(11)15)8-3-5-9(14)6-4-8/h3-7H,2,15H2,1H3

Upstream product

• 110-91-8 morpholine 
• 20992-89-6 ethyl (Z)-2-cyano-3-(p-bromophenyl)but-2-enoate 
• 99-90-1 para-bromoacetophenone 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 546064-73-7 4-(4-bromophenyl)-2-(2-cyano-acetylamino)-thiophene-3-carboxylic acid ethyl ester 
• 1194091-71-8 C₂₈H₂₄ClNO₄S 
• 1194090-91-9 2-chloro-4-hydroxy-3-(2'-methoxybiphenyl-4-yl)-5-phenyl-6,7-dihydro-thieno[2,3-b]pyridin-6-one 
• 1194090-94-2 4-hydroxy-3-(3'-hydroxymethylbiphenyl-4-yl)-5-(pyridine-3-yl)-6,7-dihydro-thieno[2,3-b]pyridin-6-one 
• 1194091-70-7 C₂₈H₂₅NO₄S 
• 1194090-93-1 4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-5-(pyridine-3-yl)-6,7-dihydro-thieno[2,3-b]pyridin-6-one 
• 1194090-92-0 4-hydroxy-3-(2'-hydroxybiphenyl-4-yl)-5-phenyl-6,7-dihydro-thieno[2,3-b]pyridin-6-one 
• 1190766-23-4 3-(4-bromophenyl)-4-hydroxy-5-(pyridin-3-yl)-6,7-dihydro-thieno[2,3-b]pyridin-6-one 
• 1190766-16-5 3-(4-bromophenyl)-4-hydroxy-5-phenyl-6,7-dihydro-thieno[2,3-b]pyridin-6-one 
• 79652-99-6 4-(4-bromophenyl)thiophen-2-amine 
• 312939-81-4 4-(4-bromophenyl)-2-(2-carboxybenzoylamino)thiophene-3-carboxylic acid ethyl ester 
• 1194091-69-4 C₂₀H₁₇BrN₂O₃S 
• 546097-25-0 C₂₁H₁₈BrNO₃S 
• 1101067-88-2 4-(4-bromophenyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-thiophene-3-carboxylic acid ethyl ester 

Relevant articles and documents

Thienopyridones as AMPK activators for the treatment of diabetes and obesity

The present invention relates to compounds that activate AMP-activated protein kinase (AMPK), including the preparation of the compounds, compositions containing the compounds and the use of the compounds in the prevention or treatment of disorders such as diabetes, metabolic syndrome, and obesity.

Pharmaceutically active compounds and methods of use

New fused thiophene compounds are provided and methods of using those compounds for a variety of therapeutic indications. Compounds of the invention are particularly useful for treatment of neuropathic pain.