379241-58-4 Usage
General Description
5-(4-Bromophenyl)thieno[2,3-d]pyrimidine-4-thiol is a chemical compound with the molecular formula C12H7BrN2S2. It is a thieno[2,3-d]pyrimidine derivative, which is a class of compounds with potential pharmaceutical applications. This specific compound contains a thiol group, a bromophenyl group, and a thieno[2,3-d]pyrimidine core. Thieno[2,3-d]pyrimidine derivatives have been studied for their potential as antiviral, anticancer, and anti-inflammatory agents, among other therapeutic properties. The presence of a bromophenyl group in this compound may also impart specific chemical and biological properties. Research on the potential uses and properties of 5-(4-Bromophenyl)thieno[2,3-d]pyrimidine-4-thiol and related compounds is ongoing.
Check Digit Verification of cas no
The CAS Registry Mumber 379241-58-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,9,2,4 and 1 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 379241-58:
(8*3)+(7*7)+(6*9)+(5*2)+(4*4)+(3*1)+(2*5)+(1*8)=174
174 % 10 = 4
So 379241-58-4 is a valid CAS Registry Number.
379241-58-4Relevant articles and documents
Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin- 4-ylthio)carboxylic acids as inhibitors of human protein kinase CK2
Golub, Andriy G.,Bdzhola, Volodymyr G.,Briukhovetska, Nadiia V.,Balanda, Anatoliy O.,Kukharenko, Olexander P.,Kotey, Igor M.,Ostrynska, Olga V.,Yarmoluk, Sergiy M.
, p. 870 - 876 (2011/04/22)
A novel series of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids has been synthesized and tested in vitro towards human protein kinase CK2. It was revealed that the most active compounds inhibiting CK2 are 3-{[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio}propanoic acid and 3-{[5-(4-ethoxyphenyl)thieno[2,3-d]pyrimidin-4-yl]thio}propanoic acid (IC 50 values are 0.1 μM and 0.125 μM, respectively). Structure-activity relationships of 28 tested thienopyrimidine derivatives have been studied and binding mode of this chemical class has been predicted. Evaluation of the inhibitors on seven protein kinases revealed considerable selectivity towards CK2.
