306956-35-4Relevant academic research and scientific papers
Structure-based design of a novel, potent, and selective inhibitor for MMP-13 utilizing NMR spectroscopy and computer-aided molecular design
Chen,Nelson,Levin,Mobilio,Moy,Nilakantan,Zask,Powers
, p. 9648 - 9654 (2000)
The high-resolution NMR solution structure of the catalytic fragment of human collagenase-3 (MMP-13) was used as a starting point for structure-based design of selective inhibitors for MMP-13. The major structural difference observed between the MMP struc
