30818-11-2

Basic information

• Product Name: Ethanone, 1-(4-piperidinyl)- (9CI)
• Synonyms: Ethanone, 1-(4-piperidinyl)- (9CI);1-Piperidin-4-yl-ethanone;Ethanone,1-(4-piperidinyl)-;1-(piperidin-4-yl)ethan-1-one
• CAS NO: 30818-11-2
• Molecular Formula: C₇H₁₃NO
• Molecular Weight: 127.18422
• Product Categories: ACETYLGROUP
• Mol File: 30818-11-2.mol

Chemical Properties

• Boiling Point: 201.6 °C at 760 mmHg
• Flash Point: 86.1 °C
• Appearance: /
• Density: 0.95 g/cm³
• Vapor Pressure: 0.305mmHg at 25°C
• Refractive Index: 1.445
• Storage Temp.: 2-8°C(protect from light)
• PKA: 9.83±0.10(Predicted)
• CAS DataBase Reference: Ethanone, 1-(4-piperidinyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(4-piperidinyl)- (9CI)(30818-11-2)
• EPA Substance Registry System: Ethanone, 1-(4-piperidinyl)- (9CI)(30818-11-2)

Safety Data

• Hazardous Substances Data: 30818-11-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Development:
Ethanone, 1-(4-piperidinyl)(9CI) is utilized as a key building block in the synthesis of various organic compounds, particularly for the development of pharmaceutical drugs. Its unique structure allows it to be a versatile component in the creation of complex molecules, contributing to the advancement of drug discovery.
Used in Central Nervous System Disorders:
In the field of medicinal chemistry, Ethanone, 1-(4-piperidinyl)(9CI) is employed as a precursor in the development of new therapeutic agents aimed at treating central nervous system disorders. Its potential applications in this area highlight its importance in the research and formulation of novel treatments for neurological conditions.
Used in Organic Chemistry:
Ethanone, 1-(4-piperidinyl)(9CI) serves as a starting material in organic chemistry, where it is used to produce a wide range of complex molecules. Its role in this discipline underscores its value in the synthesis of compounds with diverse applications across various industries.

InChI:InChI=1/C7H13NO/c1-6(9)7-2-4-8-5-3-7/h7-8H,2-5H2,1H3

Upstream product

• 498-94-2 isonipecotic acid 
• 2033-24-1 cycl-isopropylidene malonate 
• 91419-48-6 4-carbamoyl-piperidine-1-carboxylic acid tert-butyl ester 
• 91419-52-2 1-tert-butoxycarbonyl-4-cyanopiperidine 
• 39546-32-2 4-carboxamidopiperidine 
• 206989-61-9 4-acetyl-1-(t-butoxycarbonyl)piperidine 
• 136081-74-8 ethyl 1-benzoyl-4-piperidine-carboxylate 

Downstream Products

• 106243-23-6 4-(1H-imidazol-4-yl)-piperidine 
• 20691-91-2 1-(1-methylpiperidin-4-yl)ethanone 
• 1208147-47-0 C₂₅H₂₂Cl₂N₄O₂ 
• 1343349-82-5 1-(1-methanesulfonylpiperidin-4-yl)ethan-1-one 
• 527694-09-3 C₃₂H₄₅N₃O₄S 
• 455267-29-5 4-(1-amino-ethyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 609367-62-6 (R)-2-[(Benzyloxy-formyl-amino)-methyl]-hexanoic acid [(S)-1-(4-acetyl-piperidine-1-carbonyl)-2,2-dimethyl-propyl]-amide 
• 609367-76-2 [(S)-1-(4-Acetyl-piperidine-1-carbonyl)-2,2-dimethyl-propyl]-carbamic acid benzyl ester 

Relevant articles and documents

Synthesis and antibacterial evaluation of novel 2-[N-Imidoylpyrrolidinyl] carbapenems

The synthesis, antibacterial activity and DHP-susceptibility of a series of novel carbapenems, directly linked with heterocyclic moiety are described. Especially, the compounds linked pyrrolidine-carbapenem exhibited to have a good antibacterial activity against Staphylococcus aureus (MRSA) as well as Pseudomonas aeruginosa to maintain a good stability towards DHP-I.

Studies on new platelet aggregation inhibitors 1. Synthesis of 7-nitro-3,4-dihydroquinoline-2(1H)-one derivatives

A series of 6-cyclic aliphatic amino-7-nitro-3,4-dihydroquinoline-2(1H)-ones were prepared and tested for platelet aggregation inhibitory effect, cardiotonic activity and chronotropic activity. These compounds appeared to show selective inhibitory activity against platelet aggregation. Among them, 6-(4-ethoxycarbonylpiperidino)-7-nitro-3,4-dihydroquinoline-2(1H)-one (22f) showed the most potent inhibitory activity and high selectivity. A divergent synthetic route to 6-cyclic aliphatic amino-7-nitro-3,4-dihydroquinoline-2(1H)-one derivatives has also been investigated.