309243-65-0

Upstream product

• 17640-15-2 methyl cyanoformate 
• 917-54-4 methyllithium 
• 309243-64-9 (R)-4-[(tert-butyldimethylsilyl)oxy]-3-methyl-cyclohex-2-en-1-one 
• 309243-63-8 4-acetoxy-3-methyl-2-cyclohexen-1-one 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 184653-97-2 (R)-4-hydroxy-3-methyl-cyclohex-2-en-1-one 
• 57356-79-3 4-hydroxy-3-methyl-cyclohex-2-en-1-one 

Downstream Products

• 171231-07-5 (1S,5R)-cis-3-hydroxy-2,2-dimethyl-6-methylenecyclohexanemethanol 

Relevant academic research and scientific papers

Straightforward enantioselective synthesis of both enantiomers of karahana lactone using a domino ring-closure sequence

A straightforward enantioselective synthesis of both enantiomers of karahana lactone is described starting from enantiopure (R) or (S)-4-hydroxy-3-methyl-cyclohex-2-en-1-one. The key step of the sequence is an acid-induced domino reaction with three pathways running. Because of the first description of karahana lactone as a solid, the structure was secured by X-ray structural analysis. (C) 2000 Elsevier Science Ltd.