3095-81-6Relevant academic research and scientific papers
Multicolor luminescent supramolecular hydrogels based on cucurbit[8]uril and OPV derivative
Chang, Yong-Zhen,Chen, Yong,Liu, Yu
, p. 9881 - 9885 (2019)
Supramolecular hydrogels have received considerable attention because of their various fascinating applications. Herein, an alkyl chain-modified oligo(p-phenylenevinylene) (Py-OPV) derivative was synthesized. When assembled with cucurbit[7]uril, its fluor
A highly selective and sensitive fluorescent chemosensor for Hg2+ based on a pyridine-appended π-conjugated ligand
Yang, Yaping,Ni, Xin-Long,Sun, Tao,Cong, Hang,Wei, Gang
, p. 47000 - 47004 (2014)
A pyridine-appended π-conjugated ligand 1,4-bis[2-(4-pyridyl)ethenyl]benzene (bpeb) has proved to be highly selective and sensitive as a chemosensor for Hg2+ in buffered aqueous solution. Remarkable changes in the UV-vis and fluorescence emission spectra were observed upon addition of Hg2+ ions to a solution of bpeb. In particular, the interaction of the lone-pair electrons on the pyridine nitrogen with Hg2+ ions results in a significant red-shift in the fluorescence spectrum and a large Stokes shift of up to 65 nm. DFT calculations have revealed that the energy levels of the HOMO and LUMO of bpeb are critically decreased upon coordination to Hg2+ ions, thereby accounting for this red-shift of the fluorescence spectrum. Furthermore, bpeb has been shown to be applicable as a fluorescent probe for imaging Hg2+ ions in PC3 cell lines, which may help in the understanding of relevant biological processes at the molecular level. This journal is
New viologen analogs: 1,4-bis[2-(pyridin-4-yl)ethenyl]benzene quaternary salts
Gutov,Rusanov,Chepeleva,Garasevich,Ryabitskii,Chernega
, p. 1513 - 1518 (2009)
Alkylation of 1,4-bis[2-(pyridin-4-yl)ethenyl]benzene with alkyl p-toluenesulfonates and dimethyl sulfate gave new viologen analogs, 1-alkyl-4-(2-{4-[2-(1-alkylpyridinium-4-yl)ethenyl]phenyl}ethenyl)-pyridinium bis(p-toluenesulfonates) and sulfate. Their
Synthesis of some new distyrylbenzene derivatives using immobilized Pd on an NHC-functionalized MIL-101(Cr) catalyst: photophysical property evaluation, DFT and TD-DFT calculations
Niknam, Esmaeil,Mahmoodi, Ali,Panahi, Farhad,Heydari Dokoohaki, Maryam,Zolghadr, Amin Reza,Khalafi-Nezhad, Ali
, p. 12374 - 12380 (2021/04/07)
In this study the catalytic application of a heterogeneous Pd-catalyst system based on metal organic framework [Pd-NHC-MIL-101(Cr)] was investigated in the synthesis of distyrylbenzene derivatives using the Heck reaction. The Pd-NHC-MIL-101(Cr) catalyst s
Immobilized Pd on a NHC-functionalized metal-organic FrameworkMIL-101(Cr): An efficient heterogeneous catalyst in the heck and copper-free Sonogashira coupling reactions
Niknam, Esmaeil,Panahi, Farhad,Khalafi-Nezhad, Ali
supporting information, (2021/01/12)
A heterogeneous palladium catalyst system based on immobilization of palladium moieties on a N-heterocyclic carbene (NHC) modified metal organic framework (MOF) was developed for the Heck and copper-free Sonogashira coupling reactions. In order to prepare this catalyst system, first, MIL-101(Cr) was functionalized with NHC moieties through a post synthetic modification (PSM) approach, and then Pd metal was stabilized on the prepered MIL-101(Cr)-NHC substrate. This material was characterized using various microscopic and spectroscopic techniques and then was used as an efficient heterogeneous Pd catalyst system in the Heck and copper-free Sonogashira reactions. Results of the heterogeneity tests showed that the Pd-NHC-MIL-101(Cr) catalyst can efficiently catalyzed these coupling reactions heterogeneously and no remarkable changes observed in the morphology and structure of MIL-101(Cr) template during the reaction progress. Also, existence of palladium nanoparticles immobilized on the MOF structure affirmed by the TEM and XPS analysis confirmed the oxidation state of Pd. A variety of alkene and alkyne derivatives were synthesized in good to excellent yields using this heterogeneous Pd catalyst system under normal conditions. More importantly Pd-NHC-MIL-101(Cr) catalyst was simply recovered from the reaction medium without remarkable decreasing in its catalytic activities after five times of reusability. The ICP analysis showed the very low Pd and Cr metals leaching, representing high stability and applicability of this catalyst in Pd coupling reactions.
Ring-in-ring(s) complexes exhibiting tunable multicolor photoluminescence
Wu, Huang,Wang, Yu,Jones, Leighton O.,Liu, Wenqi,Song, Bo,Cui, Yunpeng,Cai, Kang,Zhang, Long,Shen, Dengke,Chen, Xiao-Yang,Jiao, Yang,Stern, Charlotte L.,Li, Xiaopeng,Schatz, George C.,Fraser Stoddart
supporting information, p. 16849 - 16860 (2020/11/09)
One ring threaded by two other rings to form a non-intertwined ternary ring-in-rings motif is a challenging task in noncovalent synthesis. Constructing multicolor photoluminescence systems with tunable properties is also a fundamental research goal, which
A Dynamic Tetracationic Macrocycle Exhibiting Photoswitchable Molecular Encapsulation
Wu, Huang,Chen, Yong,Zhang, Long,Anamimoghadam, Ommid,Shen, Dengke,Liu, Zhichang,Cai, Kang,Pezzato, Cristian,Stern, Charlotte L.,Liu, Yu,Stoddart, J. Fraser
supporting information, p. 1280 - 1289 (2019/01/14)
Designing macrocycles with appropriate molecular recognition features that allow for the integration of suitable external stimuli to control host-guest processes is a challenging endeavor which enables molecular containers to solubilize, stabilize, and separate chemical entities in an externally controllable manner. Herein, we introduce photo- and thermal-responsive elements into a semi-rigid tetracationic cyclophane, OPVEx2Box4+, that is composed of oligo(p-phenylenevinylene) pyridinium units and the biphenylene-bridged 4,4-bipyridinium extended viologens and adopts a rectangle-like geometry. It transpires that when the photoactive oligo(p-phenylenevinylene) pyridinium unit is incorporated in a macrocyclic scaffold, its reversibility is dramatically improved, and the configurations of the cyclophane can go back and forth between (EE)- and (EZ)-isomers upon alternating blue light irradiation and heating. When the macrocycle is found in its (EE)-configuration, it is capable of binding various π-electron-rich guests - e.g., anthracene and perylene - as well as π-electron-deficient guests - e.g., 9,10-anthraquinone and 5,12-tetracenequinone - through charge-transfer and van der Waals interactions. When irradiated with blue light, the (EE)-isomer of the cyclophane can be transformed successfully to the (EZ)-isomer, resulting in the switching off of the binding affinity for guest molecules, which are bound once again upon heating. The use of light and heat as external stimuli to control host-guest interactions involving a multi-responsive host and various guests provides us with a new opportunity to design and construct more-advanced molecular switches and machines.
A pyridine chain conjugated system polymer derivatives and its preparation method and application (by machine translation)
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Paragraph 0181-0186, (2019/06/07)
The invention discloses a pyridine chain conjugated system polymer derivatives and its preparation method and application, relates to the field of organic synthetic technology. The compounds of the invention have the general formula 1, formula 2, formula 3 or formula 4 four kinds of structure; wherein R1 To bromine, methyl, tert-butyl, methoxy, ester or amide group; m is 2 or 3; formula 2 R in the2 Bromo, ester group, amido group or a carboxyl group; R3 Is hydrogen, fluoro, methyl, methoxy, ester or amide; formula 3 or formula 4 in the X is a carbon atom or a nitrogen atom; R4 Hydrogen, methyl, fluorine, chlorine, bromine or nitro; Y is a carbon atom or a nitrogen atom; Z is imino or oxygen atom. The invention synthetic compounds of rotenone induced PC12 cell injury has obvious protection functions, and to α - Syn protein aggregation and fibrosis has obvious inhibition, statistical significance, may be further developed to be used for the treatment of Parkinson's drug; the general formula 1 - general formula 4 are respectively: (by machine translation)
Anti-oligomerization sheet molecules: Design, synthesis and evaluation of inhibitory activities against α-synuclein aggregation
Liu, Hao,Chen, Li,Zhou, Fei,Zhang, Yun-Xiao,Xu, Ji,Xu, Meng,Bai, Su-Ping
supporting information, p. 3089 - 3096 (2019/06/14)
Aggregation of α-synuclein (α-Syn) play a key role in the development of Parkinson Disease (PD). One of the effective approaches is to stabilize the native, monomeric protein with suitable molecule ligands. We have designed and synthesized a series of sheet-like conjugated compounds which possess different skeletons and various heteroatoms in the two blocks located at both ends of linker, which have good π-electron delocalization and high ability of hydrogen-bond formation. They have shown anti-aggregation activities in vitro towards α-Syn with IC50 down to 1.09 μM. The molecule is found binding in parallel to the NACore within NAC domain of α-Syn, interfering aggregation of NAC region within different α-Syn monomer, and further inhibiting or slowing down the formation of α-Syn oligomer nuclei at lag phase. The potential inhibitor obtained by our strategy is considered to be highly efficient to inhibit α-Syn aggregation.
Solvent-Mediated Synthesis of Cyclobutane Isomers in a Photoactive Cadmium(II) Porous Coordination Polymer
Claassens, Isabella E.,Nikolayenko, Varvara I.,Haynes, Delia A.,Barbour, Leonard J.
supporting information, p. 15563 - 15566 (2018/10/31)
Photochemical [2+2] cycloaddition of 1,4-bis[2-(4-pyridyl)ethenyl]benzene, carried out in a CdII porous coordination polymer (PCP), produces different isomeric products depending on the guest solvent present in the PCP during irradiation. The n
