309924-34-3

Upstream product

• 149540-21-6 5-(6-amino-8-bromo-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-ol 
• 14985-44-5 8-bromo-2'-deoxyadenosine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 362-03-8 3-(10H-phenothiazin-10-yl)propanoic acid 
• 1698-80-2 10H-phenothiazine-10-propanenitrile 
• 92-84-2 10H-phenothiazine 
• 129451-79-2 N-(9-{5-[bis(4-methoxyphenyl)phenylmethoxyphenyl]-4-hydroxytetrahydrofuran-2-yl}-8-bromo-9H-purin-6-yl)benzamide 
• 309924-32-1 N'-(2-propynyl)-β-(10-phenothiazinyl)propionamide 

Relevant academic research and scientific papers

Synthesis and stability of oligodeoxynucleotides containing C8-labeled 2'-deoxyadenosine: novel redox nucleobase probes for DNA-mediated charge-transfer studies.

[reaction: see text] An efficient and convenient synthetic strategy to redox-labeled C8-derivatives of 2'-deoxyadenosine is described. The Pd(0) cross-coupling chemistry is amenable to both oxidative and reductive redox probes. The corresponding phosphoramidites of phenothiazine and anthraquinone nucleosides are amenable to automated DNA synthesis. The resulting labeled oligodeoxynucleotide strands form stable B-form duplexes with melting temperatures and CD spectra similar to those of the unlabeled analogues.