31089-49-3

Usage

Uses

Used in Personal Care and Healthcare Products:
4-Benzyl-2-chlorophenol is used as an antiseptic and disinfectant for its ability to inhibit the growth of microorganisms. This makes it suitable for inclusion in products such as soaps, lotions, and mouthwashes to promote hygiene and prevent infections.
Used in Industrial and Household Product Preservation:
4-Benzyl-2-chlorophenol serves as a preservative in industrial and household products like paints and adhesives, helping to prevent spoilage and extend the shelf life of these items.
However, it is important to note that due to the potential toxicity and environmental impact of 4-benzyl-2-chlorophenol, its use is regulated in many countries to ensure safety and minimize ecological harm.

InChI:InChI=1/C13H11ClO/c14-12-9-11(6-7-13(12)15)8-10-4-2-1-3-5-10/h1-7,9,15H,8H2

Upstream product

• 95-57-8 2-monochlorophenol 
• 100-44-7 benzyl chloride 
• 100-51-6 benzyl alcohol 
• 7446-70-0 aluminium trichloride 
• 101-53-1 p-benzylphenol 
• 100-39-0 benzyl bromide 

Downstream Products

• 38932-58-0 4-benzyl-2,6-dichloro-phenol 

Relevant academic research and scientific papers

Identification, library synthesis and anti-vibriosis activity of 2-benzyl-4-chlorophenol from cultures of the marine bacterium Shewanella halifaxensis

Summer Gut Syndrome (SGS) is caused by various Vibrio bacterial species and can have negative effects on aquaculture farms worldwide. In New Zealand, SGS is caused by Vibrio harveyii infecting King Salmon (Oncorhynchus tshawytscha). To find leads for the prevention of SGS, we screened the inhibitory effects of 16 strains of Shewanella upon V. harveyii growth in competitive solid phase cultures. The detailed investigation of Shewanella halifaxensis IRL548 revealed 2-benzyl-4-chlorophenol (1), a known, commercially available antibacterial agent, as the major bioactive component. Synthesis of a small library of congeners to confirm the natural product identity and to provide a structure-activity relationship for the observed activity was also completed. Compound 1 exhibits moderate activity against two pathogenic microorganisms.

Pyrimidine derivatives and fungicides and/or acaricides containing them as active ingredient

A compound which is effective as an active ingredient of fungicides and/or acaricides, and is represented by the formula and a method for preparing the same are provided: STR1 wherein R1 and R2 are bonded together at their termini and represent trimethylene or teramethylene, R3 represents a hydrogen atom, a lower alkyl group or a halogen atom, R4 represents a hydrogen atom or a lower alkyl group, R5 represents a hydrogen atom, a lower alkyl group or a methylthio group and n represents 2 or 3.

ALKYLATION OF 2- AND 4-CHLOROPHENOLS BY ALKYL HALIDES IN THE PRESENCE OF SMALL AMOUNTS OF CATALYSTS

The alkylation of 2-chlorophenol by benzyl chloride, chlorocyclohexane, chlorocyclopentane, sec-butyl bromide, and 1- and 2-bromopentanes in the presence of 1.06.10-3 - 1.06.10-2 mole of catalyst (a Lewis acid) was investigated.Competing alkylations of chlorophenols and phenol with benzyl chloride, realized under identical conditions, showed that the reactivity of the substrate decreases in the order: phenol > 3-chlorophenol > 4-chlorophenol >= 2-chlorophenol.The ratio of the 6- and 4-isomers of benzyl-2-chlorophenols is not affected by the nature of the anion in the catalyst.During the alkylation of 4-chlorophenol with butyl bromide and bromopentane the main product is sec-alkyl-4-chlorophenol (yield 86-90percent), and 4-9percent of the alkyl-4-chlorophenol is formed.