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Benzenesulfonamide, 4-fluoro-N-(4-fluorophenyl)-, also known as 4-fluoro-N-(4-fluorophenyl)benzenesulfonamide, is a chemical compound with the molecular formula C12H8F2NO2S. It is a derivative of benzenesulfonamide, featuring two fluorine atoms attached to the benzene ring, one at the para position and the other on the phenyl group connected to the sulfonamide. Benzenesulfonamide, 4-fluoro-N-(4-fluorophenyl)- is an organic molecule that belongs to the class of sulfonamides, which are known for their diverse applications in various fields, including pharmaceuticals and agrochemicals. The presence of fluorine atoms in the molecule can significantly influence its physical and chemical properties, such as reactivity, lipophilicity, and metabolic stability, making it a potentially valuable compound for the development of new drugs or chemical intermediates.

312-58-3

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312-58-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 312-58-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,1 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 312-58:
(5*3)+(4*1)+(3*2)+(2*5)+(1*8)=43
43 % 10 = 3
So 312-58-3 is a valid CAS Registry Number.

312-58-3Relevant academic research and scientific papers

BENZENE SULFONAMIDE DERIVATIVES AND THEIR USE AS RORC MODULATORS

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Page/Page column 56, (2015/12/08)

Compounds of the formula la or lb: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, r, A, D, E, G, X1, X2, X3, X4, Y, Z, R1, R2, R3, R4, R5, R6, R7, and R8 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.

BENZYL SULFONAMIDE DERIVATIVES AS RORC MODULATORS

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Paragraph 0442, (2014/06/24)

Compounds of the formula Ia or Ib: or pharmaceutically acceptable salts thereof, wherein m, n, p, q, r, A, X1, X2, X3, X4, Y, Z, R1, R2, R3, R4, R5, R6, R7, and R8 are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.

Novel lithium and sodium salts of sulfonamides and bis(sulfonyl)imides: Synthesis and electrical conductivity

Morizur, Vincent,Olivero, Sandra,Desmurs, Jean Roger,Knauth, Philippe,Duach, Elisabet

, p. 6193 - 6197 (2015/02/19)

The preparation of new electrolytes for application in lithium or sodium batteries is described. Different salts of lithium and sodium sulfonamide and bis(sulfonyl)imide were prepared in good yields. Ionic conductivity measurements were performed on these salts and conductivities of 0.20 to 0.51 mS cm-1, comparable to those of Li-TFSI, were obtained. The best conductivity was reached for the Li+ salt of a bis(sulfonyl)imide bearing CF3 and 4-FC6H4 groups. This journal is

SUBSTITUTED SULFONAMIDE COMPOUNDS

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Page/Page column 117, (2014/04/17)

The invention is concerned with the compounds of formula (I), and salts thereof, wherein X, Y, Z, R1, R2, R3, R3, R4, R5 and R6 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of Formula (I) as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.

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