31221-06-4 Usage
Uses
Used in Cardiovascular Applications:
(2,4,6-trioxotetrahydropyrimidin-5(2H)-ylidene)diazenium is used as a nitric oxide donor for the treatment of cardiovascular diseases. Nitric oxide plays a crucial role in vasodilation, which helps to improve blood flow and reduce blood pressure.
Used in Inflammatory Disorders:
(2,4,6-trioxotetrahydropyrimidin-5(2H)-ylidene)diazenium is used as an anti-inflammatory agent for the treatment of inflammatory disorders. Nitric oxide has been shown to modulate immune responses and reduce inflammation.
Used in Neurological Disorders:
(2,4,6-trioxotetrahydropyrimidin-5(2H)-ylidene)diazenium is used as a neuroprotective agent for the treatment of neurological disorders. Nitric oxide is involved in neurotransmission and can help to protect neurons from damage.
Used in Drug Development:
(2,4,6-trioxotetrahydropyrimidin-5(2H)-ylidene)diazenium is used as a starting compound for the development of nitric oxide-based therapies. Its chemical structure and properties make it suitable for further modification and optimization to enhance its nitric oxide releasing capabilities for therapeutic purposes.
Used in Biomedical Research:
(2,4,6-trioxotetrahydropyrimidin-5(2H)-ylidene)diazenium is used as a research tool to study the role of nitric oxide in various physiological processes and to develop new therapeutic strategies for a range of conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 31221-06-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,1,2,2 and 1 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 31221-06:
(7*3)+(6*1)+(5*2)+(4*2)+(3*1)+(2*0)+(1*6)=54
54 % 10 = 4
So 31221-06-4 is a valid CAS Registry Number.
31221-06-4Relevant academic research and scientific papers
Direct Synthesis of 5-Aryl Barbituric Acids by Rhodium(II)-Catalyzed Reactions of Arenes with Diazo Compounds
Best, Daniel,Burns, David J.,Lam, Hon Wai
supporting information, p. 7410 - 7413 (2015/06/30)
A commercially available rhodium(II) complex catalyzes the direct arylation of 5-diazobarbituric acids with arenes, allowing straightforward access to 5-aryl barbituric acids. Free N-H groups are tolerated on the barbituric acid, with no complications arising from N-H insertion processes. This method was applied to the concise synthesis of a potent matrix metalloproteinase (MMP) inhibitor.
Direct ionic liquid promoted organocatalyzed diazo-transfer reactions: diversity-oriented synthesis of diazo-compounds
Ramachary, Dhevalapally B.,Narayana, Vidadala V.,Ramakumar, Kinthada
, p. 2704 - 2709 (2008/09/19)
A practical and novel ionic liquid promoted organocatalytic selective diazo-transfer process for the synthesis of highly substituted diazo-compounds in high yields is reported. The ionic liquid can be reused without affecting the reaction rates or yields over five runs.
Preparation of diazo and azo compounds using azidoformamidium salts
-
, (2008/06/13)
Preparation of diazo compounds by transfer of diazo groups to activated methylene compounds, characterized in that an azidoformamidinium salt is used as the diazo group transferring agent, and also preparation of azo compounds by this route.
