31271-86-0

Usage

Chemical structure

An indole derivative with a sulfonyl group and a carbonitrile group

Indole derivative

Contains the indole ring, which is a common structural motif in many biologically active compounds

Sulfonyl group

A functional group containing a sulfur atom bonded to two oxygen atoms (-SO2-)

Carbonitrile group

A functional group containing a carbon atom triple-bonded to a nitrogen atom (-CN)

Potential pharmaceutical applications

Known for diverse biological activities, including anti-inflammatory, analgesic, and anticancer properties

Bioactivity

The presence of the sulfonyl and carbonitrile groups may contribute to the compound's bioactivity

Further research

Additional studies are needed to fully understand the properties and potential uses in the pharmaceutical and biotechnology industries

Upstream product

• 106486-93-5 1-[(4-methylbenzene)sulfonyl]-6,7-dihydro-1H-indole-4-carbonitrile 
• 106154-13-6 1-[(4-methylbenzene)sulfonyl]-4-[(trimethylsilyl)oxy]-4,5,6,7-tetrahydro-1H-indole-4-carbonitrile 
• 91734-76-8 methyl 4-tri-n-butylstannylbenzoate 
• 167084-20-0 3-Iod-1-(4-tolylsulfonyl)indol-4-carbonitril 
• 16136-52-0 4-cyanoindole 
• 35577-89-0 1-[(4-methylbenzene)sulfonyl]-4,5,6,7-tetrahydro-1H-indol-4-one 
• 98-59-9 p-toluenesulfonyl chloride 
• 106486-94-6 4-cyano-1-(p-toluenesulfonyl)-4,5-dihydroindole 
• 76989-06-5 5-bromo-4-oxo-N-(p-toluenesulfonyl)-4,5,6,7-tetrahydroindole 
• 95969-07-6 5-chloro-4-oxo-N-(p-toluenesulfonyl)-4,5,6,7-tetrahydroindole 
• 167084-11-9 3-Iodindol-4-carbonitril 

Downstream Products

• 1313236-98-4 9-(benzo[d]oxazol-2-yl)-1-((1-tosyl-1H-indol-4-yl)methyl)-1,9-diazaspiro[5.5]undecan-2-one 
• 1145678-74-5 (1-tosyl-1H-indol-4-yl)methanamine 
• 1313236-71-3 tert-butyl 4-allyl-4-((1-tosyl-1H-indol-4-yl)methylamino)piperidine-1-carboxylate 
• 1313236-73-5 tert-butyl 4-allyl-4-(N-((1-tosyl-1H-indol-4-yl)methyl)acrylamido)piperidine-1-carboxylate 
• 1313236-75-7 tert-butyl 2-oxo-1-((1-tosyl-1H-indol-4-yl)methyl)-1,9-diazaspiro[5.5]undec-3-ene-9-carboxylate 
• 1313236-77-9 tert-butyl 2-oxo-1-((1-tosyl-1H-indol-4-yl)methyl)-1,9-diazaspiro[5.5]undecane-9-carboxylate 
• 1313236-80-4 1-((1-tosyl-1H-indol-4-yl)methyl)-1,9-diazaspiro[5.5]undecan-2-one trifluoroacetate 
• 1313236-82-6 9-(quinoxalin-2-yl)-1-((1-tosyl-1H-indol-4-yl)methyl)-1,9-diazaspiro[5.5]undecan-2-one 
• 1221233-13-1 C₁₈H₂₁NO₂SSi 
• 1221233-11-9 1-tosyl-4-(E-2-(triethylsilyl)vinyl)-1H-indole 

Relevant academic research and scientific papers

DIAZA-SPIRO[5.5]UNDECANES AS OREXIN RECEPTOR ANTAGONISTS

The invention relates to compound of the formula (I), in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.

Supramolecular Phosphorylation of Cationic Alcohols with a 3-Arylindole-4-carboxamidine Framework

Recently we reported on the synthesis of 8-phenylnaphthalene-1-carboxamidines equipped with nucleophilic side chains (1,2).In the protonated state these compounds were able to coordinate phosphoric acid diesters as ion-pair complexes and to react with the

SYNTHESIS OF 4-CYANOINDOLE FROM 4-OXO-4,5,6,7-TETRAHYDROINDOLE DERIVATIVES

4-Oxo-4,5,6,7-tetrahydroindoles are first converted to cyanohydrin silyl ethers and subsequent elimination and/or oxidation produced 4-cyanoindole.