31281-76-2

Upstream product

• 100-51-6 benzyl alcohol 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 34246-23-6 benzyl D-glucopyranoside 
• 108-24-7 acetic anhydride 
• 572-09-8 2,3,4,6-tetra-O-acetyl-D-glucopyranosyl bromide 
• 78942-86-6 2,3,4,6-tetra-O-acetyl-1-O-trifluoroacetyl-α-D-glucopyranose 
• 60-12-8 2-phenylethanol 
• 604-69-3 β-D-glucose pentaacetate 
• 4451-36-9 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl chloride 
• 4451-35-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl chloride 
• 4304-12-5 (2R,3R,4S,5S,6R)-2-(benzyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 
• 74808-10-9 2,3,4,6-tetra-O-acetyl-d-glucopyranosyl trichloroacetimidate 
• 2280-44-6 D-Glucose 
• 74808-10-9 O-(2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl)trichloroacetimidate 

Downstream Products

• 67890-29-3 benzyl 2,3,4,6-tetra-O-benzyl-β-D-gluco-pyranoside 
• 3947-62-4 2,3,4,5-tetra-O-acetyl-D-glucopyranose 
• 4304-12-5 (2R,3R,4S,5S,6R)-2-(benzyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol 
• 103130-13-8 benzyl 2,4,6-tri-O-benzyl-β-D-glucopyranoside 
• 126841-30-3 Acetic acid (2R,3R,4S,5R,6S)-3,5-diacetoxy-2-acetoxymethyl-6-(bromo-phenyl-methoxy)-tetrahydro-pyran-4-yl ester 
• 55274-63-0 (4S,5R,6R)-4,5,6-Tris-benzyloxy-5,6-dihydro-4H-pyran-2-carboxylic acid methyl ester 
• 67831-41-8 benzyl 2,3-di-O-benzyl-β-D-glucopyranoside 
• 103238-79-5 O¹,O²,O³-tribenzyl-β-D-glucopyranuronic acid 
• 42927-00-4 O¹,O²,O³-tribenzyl-β-D-glucopyranuronic acid methyl ester 
• 115193-05-0 benzyl 2,3-di-O-benzyl-4,6-O-isopropylidene-β-D-glucopyranose 
• 115175-83-2 (4aR,6R,7R,8R,8aS)-6-Benzyloxy-2,2-dimethyl-hexahydro-pyrano[3,2-d][1,3]dioxine-7,8-diol 
• 219864-64-9 (1S,3R,4R,5R,6S)-3,4,5-Tris-benzyloxy-2,7-dioxa-bicyclo[4.1.0]heptane-1-carboxylic acid methyl ester 
• 219865-23-3 (2R,4R,5R,6R)-4,5,6-Tris-benzyloxy-3-oxo-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 219864-55-8 (2R,3R,4R,5R,6R)-4,5,6-Tris-benzyloxy-3-bromo-2-hydroxy-tetrahydro-pyran-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Organocatalysis Linked to Charge-Enhanced Acidity with Superelectrophilic Traits

Hydrogen bonding is ubiquitous throughout nature and serves as a versatile platform for accessing chemical reactivity. In leveraging this force, chemists have utilized organocatalysts to expand the spectrum of chemical reactivity enabled by hydrogen bondi

INHIBITORS OF MALARIAL AND PLASMODIUM FALCIPARUM HEXOSE TRANSPORTER AND USES THEREOF

Provided are molecules capable of binding to binding pockets of Plasmodium falciparum hexose transporter (PfHT) or analogs thereof and complexes comprising the same. Also provided herein are inhibitors of PfHT, pharmaceutical compositions comprising the i

Rhamnogalacturonan II: Chemical Synthesis of a Substructure Including α-2,3-Linked Kdo**

The synthesis of a fully deprotected Kdo-containing rhamnogalacturonan II pentasaccharide is described. The strategy relies on the preparation of a suitably protected homogalacturonan tetrasaccharide backbone, through a post-glycosylation oxidation approach, and its stereoselective glycosylation with a Kdo fluoride donor.

Exploring the Biochemical Foundations of a Successful GLUT1-Targeting Strategy to BNCT: Chemical Synthesis and in Vitro Evaluation of the Entire Positional Isomer Library of ortho-Carboranylmethyl-Bearing Glucoconjugates

Boron neutron capture therapy (BNCT) is a noninvasive binary therapeutic modality applicable to the treatment of cancers. While BNCT offers a tumor-targeting selectivity that is difficult to match by other means, the last obstacles preventing the full har

Conformationally Controlled Reactivity of Carbasugars Uncovers the Choreography of Glycoside Hydrolase Catalysis

Glycoside hydrolases (GHs) catalyze hydrolyses of glycoconjugates in which the enzyme choreographs a series of conformational changes during the catalytic cycle. As a result, some GH families, including α-amylases (GH13), have their chemical steps conceal

Tea leaf perfumery precursor glucoside and synthesizing method thereof

The invention relates to a tea leaf perfumery precursor glucoside and a synthesizing method thereof. The synthesizing method comprises the following steps of synthesizing ten glucosides including aromatic alcohol ( alkanol )-beta -D-glucosides and aromatic alcohol (alkanol )-beta -D-primrose indicans. The synthesizing method disclosed by the invention is a glucoside synthesizing method which is good in selectivity, high in production rate and low in cost.

A method for one-step synthesis of peracetylated-alpha-O-benzyl saccharides

The invention relates to the technical field of chemical synthetic methods of saccharides, and particularly relates to a method for one-step synthesis of peracetylated-alpha-O-benzyl saccharides. A peracetylated monosaccharide is adopted as a donor, benzyl alcohol is adopted as a receptor, 1,2-dichloroethane is adopted as a reaction solvent, a peracetylated-alpha-O-benzyl saccharide is synthesizedthrough reaction under catalysis of ferric chloride anhydrous, and the reaction temperature is 10-40 DEG C. The method is high in regional universality, low in receptor consumption, mild in reactionconditions, high in yield, and high in stereoselectivity and can be used for large-scale production of target products. The catalyst is nontoxic and easily available.

Metal-free and VOC-free: O -glycosylation in supercritical CO2

Supercritical carbon dioxide (scCO2) is a suitable medium to perform transition metal-free glycosylation reactions in the absence of volatile organic solvents (VOCs) using glycosyl halides as glycosyl donors. The methodology described here can be applied for obtaining O-glycosides in a totally green reaction, as well as orthoesters, depending on the reaction conditions. The process is much more sensitive to temperature changes than to pressure modification, with glycosyl chlorides requiring higher temperatures to be activated than glycosyl bromides. Pivaloyl groups act as good CO2-philic units and are shown to be the best choice to obtain good stereoselectivities. The relevance of the fluid nature and supercritical conditions was also evidenced.

AuCl3-AgOTf promoted O-glycosylation using anomeric sulfoxides as glycosyl donors at room temperature

Activation of sulfoxide as glycosyl donors using AuCl3/AgOTf reagent system has been described. Under optimal reaction conditions, both armed and disarmed glycosyl sulfoxide donors were found to react with a range of primary, secondary, and tertiary alcohol acceptors, and sugar derived glycosyl acceptors to afford the corresponding glycosides in moderate to good yields with predictable selectivity. The reactions are quick (20–60 min), facile at room temperature and the reactions conditions tolerate acid sensitive groups.

Phosphoryl mannopentaose and derivatives thereof, and preparation methods and application thereof

The invention provides phosphoryl mannopentaose as shown in a formula (I) and derivatives as shown in formula (II) to (XI) of phosphoryl mannopentaose, and preparation methods thereof. According to the preparation methods, reactivity is regulated and cont