3136-02-5Relevant articles and documents
Amine functionalized polythiophenes: Synthesis and formation of chiral, ordered structures on DNA substrates
Ewbank, Paul C.,Nuding, Guido,Suenaga, Hikaru,McCullough, Richard D.,Shinkai, Seiji
, p. 155 - 157 (2001)
Highly regioregular, head-to-tail coupled, 3-(amino functionalized)-polythiophenes can be synthesized by CuO co-catalyzed Stille coupling. Salts of one example are water soluble, and become helically ordered upon addition of DNA.
Thiofunctionalization of Electron-Rich Heteroarenes through Magnesiation and Trapping with Octasulfur
Vera, Gonzalo,Mangeant, Reynald,Stiebing, Silvia,Berhault, Yohann,Fabis, Frédéric,Cailly, Thomas,Collot, Valérie
supporting information, p. 5099 - 5105 (2021/09/25)
Herein we report a site-selective and thiol-free thiofunctionalization of electron-rich heteroarenes. After a selective ortho-magnesiation, the use of S8 followed by an electrophile allows direct access to S-alkyl or -aryl derivatives. In situ oxidation provides the corresponding sulfoxide and sulfone derivatives. Applying this protocol, Cerlapirdine was prepared in 4 steps with 28% overall yield. (Figure presented.).
SMALL MOLECULE CD38 INHIBITORS AND METHODS OF USING SAME
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Sheet 8, (2013/03/26)
The invention provides methods and compositions for inhibiting CD 38 activity, and methods of treating or preventing various disorders associated with CD38 activity.
FRICTIONLESS MOLECULAR ROTARY MOTORS
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Page/Page column 30, (2010/02/17)
A rotaxane consisting of a cucurbituril and an uncharged guest molecule, having low or null affinity therebetween is provided as well as processes for providing the same. Various uses as energy converters (“frictionless” molecular motors), biochips and biosensors using the same are also provided.