313666-83-0Relevant academic research and scientific papers
A new sequential defluorination route to α-fluoro-α,β-unsaturated ketones from trifluoromethyl ketones
Hata, Hiroshi,Kobayashi, Takeshi,Amii, Hideki,Uneyama, Kenji,Welch, John T.
, p. 6099 - 6102 (2002)
α-Fluoro-α,β-unsaturated ketones were prepared from trifluoromethyl ketones via a sequence involving Mg metal promoted successive double defluorination. Trifluoromethyl ketones were transformed to β,β-difluoroenol silyl ethers which were then coupled with
