313976-85-1Relevant academic research and scientific papers
Thio- and aminocaffeine analogues as inhibitors of human monoamine oxidase
Booysen, Hermanus P.,Moraal, Christina,Terre'Blanche, Gisella,Petzer, Anél,Bergh, Jacobus J.,Petzer, Jacobus P.
experimental part, p. 7507 - 7518 (2012/01/03)
In a recent study it was shown that 8-benzyloxycaffeine analogues act as potent reversible inhibitors of human monoamine oxidase (MAO) A and B. Although the benzyloxy side chain appears to be particularly favorable for enhancing the MAO inhibition potency
Synthesis of 8-substituted xanthines and their oxidative skeleton rearrangement to 1-oxo-2,4,7,9-tetraazaspiro[4,5]dec-2-ene-6,8,10-triones
Zimmer, Hans,Amer, Adel,Baumann, Frank M.,Haecker, Michael,Hess, Christopher G. M.,Ho, Douglas,Huber, Hans J.,Koch, Klaus,Mahnke,Schumacher, Christian,Wingfield, Robert C.
, p. 2419 - 2428 (2007/10/03)
The synthesis of a number of 8-(dialkylamino)- and 8-alkoxyxanthines (3 and 6, respectively) is described. Treatment of 3 with m-chloroperoxybenzoic acid (m-CPBA) gave by a novel rearrangement 3-(disubstituted amino)-4,7,9- trimethyl-1-oxo-2,4,7,9-tetraaz
