31409-84-4

Upstream product

• 100-52-7 benzaldehyde 
• 134-81-6 benzil 
• 106-40-1 4-bromo-aniline 
• 501-65-5 diphenyl acetylene 
• 119-53-9 2-hydroxy-2-phenylacetophenone 

Downstream Products

• 950855-69-3 C₅₁H₃₄N₂ 

Relevant academic research and scientific papers

Facile fabrication of porous magnetic covalent organic frameworks as robust platform for multicomponent reaction

The design of cheap yet efficient nanoporous magnetic catalysts for the environmentally benign process's widespread application is an extremely attractive, challenging chemical research field. A novel porous magnetic covalent organic framework was prepared by the condensation reaction of melamine and terephthaladehyde on the surface of 3,4-dihydroxybenzaldehyde coated magnetic Fe3O4 nanoparticles COF@Fe3O4 under hydrothermal conditions for the first time. The high surface area magnetic COF could exhibit superior catalytic activity for sustainable synthesis of trisubstituted and tetrasubstituted imidazoles and pyrroles in good to excellent yields in PEG as solvent under environmentally friendly, ambient conditions and making the overall process economical, efficient, and green. The retrievable catalyst in PEG is general and applicable to a broad substrate scope and functional group compatibility. The structure and morphology of the COF@Fe3O4 were characterized by FTIR, XRD, EDX, and SEM spectroscopy. The COF@Fe3O4 magnetic catalyst was recovered by an external magnet and used for several cycles without significant catalytic activity loss.

Five-membered heterocyclic derivative and organic electroluminescent device thereof

The invention provides a five-membered heterocyclic derivative and an organic electroluminescent device thereof, and relates to the technical field of organic photoelectric materials. The five-membered heterocyclic derivative is formed by combining a five-membered nitrogen-containing heterocycle and a rigid large group, and the specific structure enables the five-membered heterocyclic derivative to have good electron transport performance, high glass transition temperature and thermal stability, strengthens the rigidity and asymmetry of molecules, avoids intermolecular aggregation, and has non-crystalliability between molecules. The utility model has the advantages of uneasy aggregation and good film forming performance. The organic electroluminescent device manufactured by using the derivative has the characteristics of good photoelectric property, low driving voltage, high luminous efficiency, long service life and the like.

Synthesis of imidazole derivatives and the spectral characterization of the binding properties towards human serum albumin

Small molecular drugs that can combine with target proteins specifically, and then block relative signal pathway, finally obtain the purpose of treatment. For this reason, the synthesis of novel imidazole derivatives was described and this study explored

One-pot synthesis of 1,2,4,5-tetrasubstituted imidazoles in ionic liquid

The four-component condensation of benzil, aromatic aldehyde, primary amine, and ammonium acetate catalyzed by TFA in ionic liquid [Bpy]BF4 at 80C provided 1,2,4,5-tetrasubstituted imidazoles in moderate to high yields.

A facile one-pot synthesis of tetrasubstituted imidazoles catalyzed by eutectic mixture stabilized ferrofluid

A robust and simple one-pot four component reaction for the efficient synthesis of tetrasubstituted imidazoles has been developed. In the presence of eutectic mixture stabilized iron oxide nanoparticles, the four-component reaction of aldehydes, amines, ammonium acetate, and 1,2-diphenylethane-1,2- dione proceeds smoothly at 60 °C to give a range of imidazole derivatives in moderate to good yields. Target compounds were obtained in high yields and high purity after recrystallization from ethanol.

Metal-free, acid-promoted synthesis of imidazole derivatives via a multicomponent reaction

An expedient and metal-free synthetic route has been developed for the construction of tri- and tetrasubstituted imidazole derivatives via acid promoted multicomponent reaction methodology. The reaction proceeded smoothly with a range of functionalities to produce the imidazole scaffolds in good to excellent yields.

Clay supported titanium catalyst for the solvent free synthesis of tetrasubstituted imidazoles and benzimidazoles

A series of clay supported metal containing catalysts were prepared and their catalytic performance was evaluated in the synthesis of tetrasubstitued imidazoles under solvent free condition. It was found that K10 supported titanium catalyst showed higher activity compared to other catalysts. The catalysts were characterized by FTIR, XRD, TG/DTA, BET surface area and SEM. The general applicability of the method was demonstrated for the synthesis of tetra- substituted imidazoles from aldehydes and amines containing various electron donating and electron withdrawing substituents. The diversity of the catalyst was studied by synthesis of benzimidazoles and quinoxalines. The mechanism of formation of the products is explained in detail. The catalyst was found to be active for three cycles.

NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME

Provided are a novel nitrogen-containing heterocyclic derivative having a specific structure and an organic electroluminescence device having an organic thin film layer composed of one or a plurality of layers including at least a light emitting layer and