31431-17-1

Usage

Uses

Used in Pharmaceutical Industry:
4,4'-DICHLORO-3-NITROBENZOPHENONE is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its versatile structure allows for the development of new drugs with potential therapeutic applications.
Used in Dye and Pigment Industry:
4,4'-DICHLORO-3-NITROBENZOPHENONE is used as a building block in the production of dyes and pigments. Its unique chemical properties contribute to the color and stability of these products.
Used in Fine Chemicals Industry:
4,4'-DICHLORO-3-NITROBENZOPHENONE is used as an intermediate in the synthesis of other fine chemicals, such as fragrances and flavorings, due to its versatile chemical structure.
Used in Antimicrobial Applications:
4,4'-DICHLORO-3-NITROBENZOPHENONE is used as an antimicrobial agent in various industrial applications, such as in the production of coatings, adhesives, and sealants, to prevent the growth of microorganisms and extend the product's shelf life.
Used in Photoinitiating Applications:
4,4'-DICHLORO-3-NITROBENZOPHENONE is used as a photoinitiator in the curing of UV-curable coatings and inks. Its ability to absorb UV light and generate free radicals enables rapid curing and improved performance of these materials.
Safety Precautions:
Due to its harmful nature if ingested or inhaled, and its potential to cause skin and eye irritation, proper safety precautions should be taken when handling 4,4'-DICHLORO-3-NITROBENZOPHENONE. This includes wearing appropriate personal protective equipment, such as gloves, goggles, and a respirator, and following proper handling and disposal procedures.

InChI:InChI=1/C13H7Cl2NO3/c14-10-4-1-8(2-5-10)13(17)9-3-6-11(15)12(7-9)16(18)19/h1-7H

Upstream product

• 90-98-2 4,4'-Dichlorobenzophenone 
• 108-90-7 chlorobenzene 
• 38818-50-7 4-chloro-3-nitro-benzoyl chloride 

Downstream Products

• 247153-23-7 6-{(4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl}-1H-benzo[d][1,2,3]triazole 
• 854534-81-9 1,2-diamino-4-{(4-chlorophenyl)(1H-1,2,4-triazol-1-yl)-methyl}benzene 
• 1285819-62-6 4-{(4-chlorophenyl)(4H-1,2,4-triazol-4-yl)methyl}-1,2-di(tert-butoxycarbonylamino)benzene 
• 1285819-61-5 4-{(4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl}-1,2-di(tert-butoxycarbonylamino)benzene 
• 1285819-58-0 4'-chloro-3,4-di(tert-butoxycarbonylamino)benzhydrol 
• 1285819-57-9 4'-chloro-3,4-di(tert-butoxycarbonylamino)benzophenone 
• 1285819-56-8 4-azido-4'-chloro-3-nitrobenzophenone 
• 1285819-60-4 4-(chloro(4-chlorophenyl)methyl)-1,2-di(tert-butoxycarbonylamino)benzene 
• 1285819-59-1 (3,4-bis(tert-butoxycarbonylamino)phenyl)(4-chlorophenyl)methyl methanesulfonate 
• 1285819-64-8 (R)-6-((4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl)-1H-benzo[d][1,2,3]-triazole 
• 42754-54-1 3,4-diamino-4'-chlorobenzophenone 
• 50297-00-2 4,4'-bis-acetylamino-3,3'-dinitro-benzophenone 
• 19014-16-5 4,4'-diamino-3,3'-dinitrobenzophenone 
• 215959-34-5 3,3-Dibromo-6-(4-chloro-benzoyl)-1,3-dihydro-indol-2-one 

Relevant academic research and scientific papers

6-ALKENYL AND 6-PHENYLALKYL SUBSTITUTED 2-QUINOLINONES AND 2-QUINOXALINONES AS POLY(ADP-RIBOSE) POLYMERASE INHIBITORS

The present invention provides compounds of formula (I) and compounds of formula (I), (VII-a), as well as pharmaceutical compositions comprising said compounds and their use as PARP inhibitors wherein n, R1, R2, R3, R4, R5, R6, R7, Re, Rd and X have defined meanings.

An improved procedure for the regiospecific synthesis of electron deficient 4- and 6-substituted isatins

The regiospecific synthesis of 4- and 6-substituted isatins 5a-g in four steps from halonitrobenzenes 1a-g has been investigated for a variety of substrates (Scheme 1). The procedure makes use of readily available, easily handled materials and in most cases purification of neither intermediates nor final products is required. Yields of isatins are between 26 and 75% (Table 1). Improved yields of known isatins are reported as well as the syntheses of previously unreported isatins. This method, taken together with known procedures, provides for the synthesis of the full complement of isatin regioisomers.

Synthesis and anthelminthic acitivity of alkyl-(5-acyl-1-benzimidazol-2-yl) carbamates

A series of alkyl-(5-acyl-l-H-benzimidazol-2-yl)-carbamates were prepared and screened for anthelminthic activity. Some of them were found to be fully active at low, atoxic oral dose levels against gastro-intestinal nematodes. The activity against Syphacia muris and Strongyloides ratta is indicated. From these studies methyl (5-benzoyl-1-H-benzimidazol-2-yl) carbamate (mebendazole) and methyl [5-(4-fluorobenzoyl)-1-H-benzimidazol-2-yl]carbamate (flubendazole) were selected for detailed investigation.