31431-17-1

Basic information

• Product Name: 4,4'-DICHLORO-3-NITROBENZOPHENONE
• Synonyms: 4,4'-DICHLORO-3-NITROBENZOPHENONE;4,4-DICHLORO-3-NITROBENZOPHENONE;(4-chloro-3-nitro-phenyl)-(4-chloro-phenyl)-methanone
• CAS NO: 31431-17-1
• Molecular Formula: C₁₃H₇Cl₂NO₃
• Molecular Weight: 296.11
• Mol File: 31431-17-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 86-90 °C(lit.)
• Boiling Point: 446.9°C at 760 mmHg
• Flash Point: 224.1°C
• Appearance: /
• Density: 1.456g/cm³
• Vapor Pressure: 3.52E-08mmHg at 25°C
• Refractive Index: 1.63
• CAS DataBase Reference: 4,4'-DICHLORO-3-NITROBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-DICHLORO-3-NITROBENZOPHENONE(31431-17-1)
• EPA Substance Registry System: 4,4'-DICHLORO-3-NITROBENZOPHENONE(31431-17-1)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 31431-17-1(Hazardous Substances Data)

Usage

General Description

4,4'-DICHLORO-3-NITROBENZOPHENONE, also known as 3-nitro-4,4'-dichlorobenzophenone, is a chemical compound with the molecular formula C13H8Cl2NO3. It is a yellow crystalline solid that is used in the synthesis of pharmaceuticals and other organic compounds. This chemical is a versatile building block in organic synthesis, commonly used as an intermediate in the production of dyes, pigments, and other fine chemicals. It is also known for its antimicrobial and photoinitiating properties, making it useful in various industrial applications. Additionally, 4,4'-DICHLORO-3-NITROBENZOPHENONE is considered to be harmful if ingested or inhaled, and is a skin and eye irritant. Therefore, proper safety precautions should be taken when handling this compound.

InChI:InChI=1/C13H7Cl2NO3/c14-10-4-1-8(2-5-10)13(17)9-3-6-11(15)12(7-9)16(18)19/h1-7H

Upstream product

• 108-90-7 chlorobenzene 
• 38818-50-7 4-chloro-3-nitro-benzoyl chloride 
• 90-98-2 4,4'-Dichlorobenzophenone 

Downstream Products

• 215959-23-2 2-[4-(4-Chloro-benzoyl)-2-nitro-phenyl]-malonic acid diethyl ester 
• 1285819-64-8 (R)-6-((4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl)-1H-benzo[d][1,2,3]-triazole 
• 1285819-60-4 4-(chloro(4-chlorophenyl)methyl)-1,2-di(tert-butoxycarbonylamino)benzene 
• 1285819-59-1 (3,4-bis(tert-butoxycarbonylamino)phenyl)(4-chlorophenyl)methyl methanesulfonate 
• 1285819-56-8 4-azido-4'-chloro-3-nitrobenzophenone 
• 1285819-57-9 4'-chloro-3,4-di(tert-butoxycarbonylamino)benzophenone 
• 1285819-58-0 4'-chloro-3,4-di(tert-butoxycarbonylamino)benzhydrol 
• 1285819-62-6 4-{(4-chlorophenyl)(4H-1,2,4-triazol-4-yl)methyl}-1,2-di(tert-butoxycarbonylamino)benzene 
• 1285819-61-5 4-{(4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl}-1,2-di(tert-butoxycarbonylamino)benzene 
• 854534-81-9 1,2-diamino-4-{(4-chlorophenyl)(1H-1,2,4-triazol-1-yl)-methyl}benzene 
• 247153-23-7 6-{(4-chlorophenyl)(1H-1,2,4-triazol-1-yl)methyl}-1H-benzo[d][1,2,3]triazole 
• 42754-54-1 3,4-diamino-4'-chlorobenzophenone 
• 50297-00-2 4,4'-bis-acetylamino-3,3'-dinitro-benzophenone 
• 19014-16-5 4,4'-diamino-3,3'-dinitrobenzophenone 

Relevant articles and documents

6-ALKENYL AND 6-PHENYLALKYL SUBSTITUTED 2-QUINOLINONES AND 2-QUINOXALINONES AS POLY(ADP-RIBOSE) POLYMERASE INHIBITORS

The present invention provides compounds of formula (I) and compounds of formula (I), (VII-a), as well as pharmaceutical compositions comprising said compounds and their use as PARP inhibitors wherein n, R1, R2, R3, R4, R5, R6, R7, Re, Rd and X have defined meanings.

Synthesis and anthelminthic acitivity of alkyl-(5-acyl-1-benzimidazol-2-yl) carbamates

A series of alkyl-(5-acyl-l-H-benzimidazol-2-yl)-carbamates were prepared and screened for anthelminthic activity. Some of them were found to be fully active at low, atoxic oral dose levels against gastro-intestinal nematodes. The activity against Syphacia muris and Strongyloides ratta is indicated. From these studies methyl (5-benzoyl-1-H-benzimidazol-2-yl) carbamate (mebendazole) and methyl [5-(4-fluorobenzoyl)-1-H-benzimidazol-2-yl]carbamate (flubendazole) were selected for detailed investigation.