31456-95-8

Basic information

• Product Name: methyl 4-methoxy-2-(prop-2-en-1-yloxy)benzoate
• CAS NO: 31456-95-8
• Molecular Formula: C₁₂H₁₄O₄
• Molecular Weight: 222.2372
• Mol File: 31456-95-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 330.432°C at 760 mmHg
• Flash Point: 144.654°C
• Density: 1.092g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.505
• CAS DataBase Reference: methyl 4-methoxy-2-(prop-2-en-1-yloxy)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-methoxy-2-(prop-2-en-1-yloxy)benzoate(31456-95-8)
• EPA Substance Registry System: methyl 4-methoxy-2-(prop-2-en-1-yloxy)benzoate(31456-95-8)

Safety Data

• Hazardous Substances Data: 31456-95-8(Hazardous Substances Data)

Upstream product

• 5446-02-6 4-methoxymethylsalicylate 
• 107-05-1 3-chloroprop-1-ene 
• 2237-36-7 4-methoxysalicylic acid 
• 106-95-6 allyl bromide 

Downstream Products

• 31457-00-8 methyl 3-allyl-2-hydroxy-4-methoxybenzoate 
• 668455-70-7 2-(allyloxy)-4-methoxybenzoic acid 
• 5446-02-6 4-methoxymethylsalicylate 
• 71186-58-8 2-allyloxy-4-methoxybenzaldehyde 
• 1207288-79-6 methyl 3-(2-(allyloxy)-4-methoxyphenyl)propiolate 
• 1207288-78-5 2-(allyloxy)-1-(2,2-dibromovinyl)-4-methoxybenzene 
• 1207288-77-4 (2-(allyloxy)-4-methoxyphenyl)methanol 
• 1207288-80-9 3-(2-(allyloxy)-4-methoxyphenyl)propiolic acid 
• 13677-76-4 2-allyl-5-methoxyphenol 
• 165258-33-3 N,N-Diethyl-2-<(tert-butyldimethylsilyl)oxy>-6-formyl-4-methoxy-5-methyl-3-(prop-2-enyl)benzamide 
• 165258-34-4 N,N-Diethyl-2-<(tert-butyldimethylsilyl)oxy>-6-hydroxymethyl-4-methoxy-5-methyl-3-(prop-2-enyl)benzamide 
• 165258-28-6 N,N-Diethyl-2-<(tert-butyldimethylsilyl)oxy>-6-deutero-4-methoxy-3-(prop-2-enyl)benzamide 
• 165258-26-4 N,N-Diethyl-5-bromo-6-deutero-2-(methoxy-d3)-4-methoxy-3-(prop-2-enyl)benzamide 
• 165258-22-0 N,N-Diethyl-5-bromo-2-<(tert-butyldimethylsilyl)oxy>-4-methoxy-3-(prop-2-enyl)benzamide 

Relevant articles and documents

Oxidative cyclization of alkenoic acids promoted by AgOAc

Alkenoic acids derived from salicylic acid and analogues undergo an unexpected oxidative cyclization process triggered by AgOAc leading to 4H-benzo[d][1,3]dioxin-4-ones. The process is affected by the substitution on the aryl and the allyl units.

INDOLES HAVING ANTI-DIABETIC ACTIVITY

Indoles of Formula (I) having -X-aryl-(CH2)x#191-oxazolidinedione and -X-heteroaryl-(CH2)X-oxazolidinedione substituents on the N atom of the indole ring, where x is 0 or 1, and -X-is a bond or -CH2-, and their thiazolidinedione analogs, are PPAR gamma agonists or partial agonists and are useful in the treatment and control of type II diabetes, including hyperglycemia, dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.

Synthesis and modeling studies with monocyclic analogues of mycophenolic acid

Two stepwise procedures, developed for the introduction of the (E)-4- methyl-4-hexenoic acid side chain of mycophenolic acid, were used in the synthesis of monocyclic mycophenolic acid analogues 2a-i. The derivatives with a methyl group or hydrogen at C-4 and lacking the lactone moiety were much less cytotoxic than mycophenolic acid. The menocyclic analogues with a C-4 chloro group did show some activity, albeit much less than mycophenolic acid. The observed differences in potency are rationalized by semiempirical calculations of intramolecular H-bonds.