31600-47-2Relevant articles and documents
Reaction of Carbenes with Cyclic Ethers in the Presence of Nucleophiles. A Three-Component Coupling Reaction
Oku, Akira,Kimura, Kenji,Ohwaki, Shigeyoshi
, p. 391 - 397 (2007/10/02)
Ternary reaction systems consisting of a carbene , a cyclic ether (THF, THP) and a protic nucleophile (alcohol, water, carboxylic acid, thiol, or amine) give the corresponding three-component coupling products which are produced via ethereal oxonium ylide intermediates.The mechanism leading to the product formation has been studied in which protonation of carbenes is excluded.