316148-59-1

Basic information

• Product Name: 1H-Imidazole-5-methanol, 4-(1,1-dimethyl-2-propen-1-yl)-
• Synonyms: 1H-Imidazole-5-methanol, 4-(1,1-dimethyl-2-propen-1-yl)-;1H-IMidazole-4-Methanol, 5-(1,1-diMethyl-2-propenyl)-
• CAS NO: 316148-59-1
• Molecular Formula: C9H14N2O
• Molecular Weight: 166.22
• Mol File: 316148-59-1.mol
• Article Data: 6

Chemical Properties

• Melting Point: 171-173 °C
• Boiling Point: 344.9±32.0 °C(Predicted)
• Appearance: /
• Density: 1.085±0.06 g/cm3(Predicted)
• PKA: 13.58±0.10(Predicted)
• CAS DataBase Reference: 1H-Imidazole-5-methanol, 4-(1,1-dimethyl-2-propen-1-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole-5-methanol, 4-(1,1-dimethyl-2-propen-1-yl)-(316148-59-1)
• EPA Substance Registry System: 1H-Imidazole-5-methanol, 4-(1,1-dimethyl-2-propen-1-yl)-(316148-59-1)

Safety Data

• Hazardous Substances Data: 316148-59-1(Hazardous Substances Data)

Upstream product

• 870-63-3 prenyl bromide 
• 316148-56-8 ethyl 2,2-dimethyl-3-(4-toluenesulfonyloxy)butanoate 
• 316148-57-9 ethyl 2-chloro-3-oxo-4,4-dimethyl-5-hexenoate 
• 66248-79-1 ethyl 4,4-dimethyl-3-oxo-hex-5-enoate 
• 7505-94-4 ethyl 3-hydroxy-2,2-dimethylbutanoate 
• 58544-20-0 ethyl 2,2-dimethyl-3-butenoate 
• 57690-96-7 2,2-dimethylbut-3-enoyl chloride 
• 10276-09-2 2,2-dimethyl-but-3-enoic acid 
• 316148-58-0 ethyl 5-(1,1-dimethyl-2-propenyl)imidazole-4-carboxylate 
• 714273-85-5 2,2-dimethyl-3-(toluene-4-sulfonyloxy)-butyric acid methyl ester 
• 19757-86-9 methyl 2,2-dimethyl-3-pentenoate 
• 69737-23-1 methyl 3-hydroxy-2,2-dimethylbutanoate 

Downstream Products

• 316148-60-4 5-(1,1-dimethyl-2-propenyl)imidazole-4-carbaldehyde 
• 316148-60-4 5-(2-methylbut-3-en-2-yl)-1H-imidazole-4-carbaldehyde 
• 714273-82-2 1-acetyl-3-{(Z)-1-[5-(1,1-dimethyl-2-propenyl)-1H-4-imidazolyl]methylidene}-2,5-piperazinedione 
• 351325-37-6 3Z-benzylidene-6Z-[[5-(1,1-dimethyl-2-propenyl)-1H-imidazol-4-yl]methylene]-2,5-piperazinedione 
• 507485-39-4 3-E-benzylidene-6-[5-(1,1-dimethylallyl)-1H-imidazol-4-Z-ylmethylene]-piperazine-2,5-dione 

Relevant articles and documents

ANALOGS OF DEHYDROPHENYLAHISTINS

Analogs of dehydrophenylahistins are disclosed as are methods for making such compounds. Compositions and methods for treating various disease conditions including cancer and non-cancer diseases associated with vascular proliferation are also disclosed.

ANALOGS OF DEHYDROPHENYLAHISTINS AND THEIR THEAPEUTIC USE

Compounds represented by the following structure (II) are disclosed: as are methods for making such compounds. Compositions and methods for treating various disease conditions including cancer and non-cancer diseases associated with vascular proliferation are also disclosed.

A remarkable ring contraction en route to the chartelline alkaloids

Weinheim (Chemical Equation Presented) One-of-a-kind. A bromine-induced rearrangement has been designed for the formation of the spiro-β-lactam ring present in the structurally unique chartelline alkaloids (see picture of chartelline A). This method is used in combination with others to provide rapid access to the carbocyclic skeletons of the chartelline, securine, and securamine alkaloids.