316148-60-4

Basic information

• Product Name: 1H-Imidazole-5-carboxaldehyde, 4-(1,1-dimethyl-2-propen-1-yl)-
• Synonyms: 1H-Imidazole-5-carboxaldehyde, 4-(1,1-dimethyl-2-propen-1-yl)-;1H-IMidazole-4-carboxaldehyde, 5-(1,1-diMethyl-2-propenyl)-
• CAS NO: 316148-60-4
• Molecular Formula: C₉H₁₂N₂O
• Molecular Weight: 164.2
• Mol File: 316148-60-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 109-111 °C
• Boiling Point: 352.1±30.0 °C(Predicted)
• Appearance: /
• Density: 1.087±0.06 g/cm3(Predicted)
• PKA: 11.20±0.10(Predicted)
• CAS DataBase Reference: 1H-Imidazole-5-carboxaldehyde, 4-(1,1-dimethyl-2-propen-1-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole-5-carboxaldehyde, 4-(1,1-dimethyl-2-propen-1-yl)-(316148-60-4)
• EPA Substance Registry System: 1H-Imidazole-5-carboxaldehyde, 4-(1,1-dimethyl-2-propen-1-yl)-(316148-60-4)

Safety Data

• Hazardous Substances Data: 316148-60-4(Hazardous Substances Data)

Upstream product

• 316148-59-1 (5-(1,1-dimethyl-2-propenyl)imidazole-4-yl)methanol 
• 316148-59-1 [5-(1,1-dimethyl-allyl)-1H-imidazol-4-yl]-methanol 
• 714273-85-5 2,2-dimethyl-3-(toluene-4-sulfonyloxy)-butyric acid methyl ester 
• 19757-86-9 methyl 2,2-dimethyl-3-pentenoate 
• 69737-23-1 methyl 3-hydroxy-2,2-dimethylbutanoate 
• 316148-56-8 ethyl 2,2-dimethyl-3-(4-toluenesulfonyloxy)butanoate 
• 316148-58-0 ethyl 5-(1,1-dimethyl-2-propenyl)imidazole-4-carboxylate 
• 316148-57-9 ethyl 2-chloro-3-oxo-4,4-dimethyl-5-hexenoate 
• 66248-79-1 ethyl 4,4-dimethyl-3-oxo-hex-5-enoate 
• 7505-94-4 ethyl 3-hydroxy-2,2-dimethylbutanoate 
• 58544-20-0 ethyl 2,2-dimethyl-3-butenoate 
• 57690-96-7 2,2-dimethylbut-3-enoyl chloride 
• 10276-09-2 2,2-dimethyl-but-3-enoic acid 

Downstream Products

• 862908-19-8 C₂₆H₃₄N₄O₅ 
• 351325-37-6 3Z-benzylidene-6Z-[[5-(1,1-dimethyl-2-propenyl)-1H-imidazol-4-yl]methylene]-2,5-piperazinedione 
• 507485-39-4 3-E-benzylidene-6-[5-(1,1-dimethylallyl)-1H-imidazol-4-Z-ylmethylene]-piperazine-2,5-dione 
• 714273-82-2 1-acetyl-3-{(Z)-1-[5-(1,1-dimethyl-2-propenyl)-1H-4-imidazolyl]methylidene}-2,5-piperazinedione 

Relevant articles and documents

ANALOGS OF DEHYDROPHENYLAHISTINS

Analogs of dehydrophenylahistins are disclosed as are methods for making such compounds. Compositions and methods for treating various disease conditions including cancer and non-cancer diseases associated with vascular proliferation are also disclosed.

ANALOGS OF DEHYDROPHENYLAHISTINS AND THEIR THEAPEUTIC USE

Compounds represented by the following structure (II) are disclosed: as are methods for making such compounds. Compositions and methods for treating various disease conditions including cancer and non-cancer diseases associated with vascular proliferation are also disclosed.

Total synthesis of anti-microtubule diketopiperazine derivatives: Phenylahistin and aurantiamine

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