31641-65-3

Basic information

• Product Name: N1-(1,1,1-TRIPHENYL-LAMBDA5-PHOSPHANYLIDENE)-4-CHLOROANILINE
• Synonyms: N1-(1,1,1-TRIPHENYL-LAMBDA5-PHOSPHANYLIDENE)-4-CHLOROANILINE;N-(4-CHLOROPHENYL)-P,P,P-TRIPHENYLPHOSPHINE IMIDE
• CAS NO: 31641-65-3
• Molecular Formula: C₂₄H₁₉ClNP
• Molecular Weight: 387.84
• Mol File: 31641-65-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 533.1°Cat760mmHg
• Flash Point: 276.2°C
• Appearance: /
• Density: 1.14g/cm³
• Vapor Pressure: 6.6E-11mmHg at 25°C
• Refractive Index: 1.609
• CAS DataBase Reference: N1-(1,1,1-TRIPHENYL-LAMBDA5-PHOSPHANYLIDENE)-4-CHLOROANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: N1-(1,1,1-TRIPHENYL-LAMBDA5-PHOSPHANYLIDENE)-4-CHLOROANILINE(31641-65-3)
• EPA Substance Registry System: N1-(1,1,1-TRIPHENYL-LAMBDA5-PHOSPHANYLIDENE)-4-CHLOROANILINE(31641-65-3)

Safety Data

• Hazardous Substances Data: 31641-65-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C24H19ClNP/c25-20-16-18-21(19-17-20)26-27(22-10-4-1-5-11-22,23-12-6-2-7-13-23)24-14-8-3-9-15-24/h1-19H

Upstream product

• 106-47-8 4-chloro-aniline 
• 2526-64-9 dichlorotriphenylphosphorane 
• 3296-05-7 1-azido-4-chlorobenzene 
• 603-35-0 triphenylphosphine 
• 5758-24-7 bromotriphenylphosphonium bromide 
• 2325-27-1 N-phenyltriphenyliminophosphorane 
• 1034-39-5 dibromotriphenylphosphorane 

Downstream Products

• 105141-09-1 1-<1-(4-Chlorphenylimino)-3-hydroxy-2,3-bis(4-methoxyphenyl)-2-propenyl>-2-(pyrrolidino)-1-cyclopenten 
• 105141-08-0 1-<1-(4-Chlorphenylimino)-3-hydroxy-2,3-bis(4-methylphenyl)-2-propenyl>-2-pyrrolidino-1-cyclopenten 
• 105141-06-8 2,3-Bis(4-chlorphenyl)-4-(4-chlorphenylimino)-5,6,7,8-tetrahydro-4H-benzopyran 
• 105141-07-9 4-(4-Chlorphenylimino)-5,6,7,8-tetrahydro-2,3-bis(4-methylphenyl)-4H-1-benzopyran 
• 93619-37-5 5,7-diphenyl-1,3,4-oxadiazolo<3,2-a>pyridinylium-2-(4-chlorophenyl)aminide 
• 838-98-2 bis-(4-chloro-phenyl)-carbodiimide 
• 76746-80-0 1-benzyl-3-(4-chlorophenyl)carbodiimide 
• 54346-54-2 7-chloro-1,3-diphenyl-1,4-dihydrobenzo[e][1,2,4]triazin-4-yl 
• 244243-10-5 [Hg₂Cl₄((C₆H₅)3PNC₆H₄Cl)2] 
• 244243-11-6 [Hg₂Br₄((C₆H₅)3PNC₆H₄Cl)2] 
• 1021153-73-0 C₂₀H₁₆Cl₂N₂O 
• 932-96-7 N-methyl(p-chloroaniline) 
• 93619-62-6 N-(4-Chloro-benzyl)-N'-(4-chloro-phenyl)-N''-(2-oxo-4,6-diphenyl-2H-pyridin-1-yl)-guanidine 
• 105141-11-5 4-(4-Chlorphenylimino)-4,5,6,7-tetrahydro-2,3-bis(4-methoxyphenyl)cyclopentapyran 

Relevant articles and documents

Staudinger reaction using 2,6-dichlorophenyl azide derivatives for robust aza-ylide formation applicable to bioconjugation in living cells

Efficient formation of water- and air-stable aza-ylides has been achieved using the Staudinger reaction between electron-deficient aromatic azides such as 2,6-dichlorophenyl azide and triarylphosphines. The reaction proceeds rapidly and has been successfully applied to chemical modification of proteins in living cells.

Selective synthesis of 4-alkylidene-β-lactams and N,N′- diarylamidines from azides and aryloxyacetyl chlorides via a ketenimine-participating one-pot cascade process

(Chemical Equation Presented) A one-pot cascade approach to 4-alkylidene-β-lactams and N,N-diarylamidines from aryl azides and aryloxyacetyl chlorides has been developed. The chemical outcome of the reaction can be controlled selectively by an appropriate choice of the stoichiometric ratio of different substrates and reagents. The products should find use in pharmaceutical discovery, especially in the development of new antimicrobial agents against multidrug-resistant pathogens.

Innovative synthesis of 4-carbaldehydepyrrolin-2-ones by zwitterionic rhodium catalyzed chemo- and regioselective tandem cyclohydrocarbonylation/CO insertion of α-imino alkynes

The tandem cyclohydrocarbonylative/CO insertion of α-imino alkynes employs CO, H2, and catalytic quantities of zwitterionic rhodium complex (η6-C6H5 BPh3)-Rh+(1,5-COD) and triphenyl phosphite affording aldehyde substituted pyrrolinones in 67-82% yields. This unique transformation is readily applied to imino alkynes containing alkyl, alkoxyl, vinyl, and aryl substituents. The ability to prepare highly functionalized pyrrolinones makes this an attractive route to these important and versatile pharmaceuticals.