3174-90-1

Upstream product

• 1122-85-6 phenyl cyanate 
• 108-95-2 phenol 

Downstream Products

• 3171-13-9 C₁₄H₁₃N₃O₃ 
• 3171-14-0 5-(4-chloro-anilino)-[1,2,4]thiadiazol-3-one 
• 3171-16-2 5-(3-chloro-anilino)-[1,2,4]thiadiazol-3-one 
• 3171-15-1 5-(4-nitro-anilino)-[1,2,4]thiadiazol-3-one 
• 3171-00-4 O-Methylmercaptocarbonyl- 
• 3171-07-1 3-phenoxy-[1,2,4]oxadiazol-5-ol 
• 82849-47-6 1-chloro-1-phenoxy-2-(carbomethoxy)cyclopropane 
• 82849-46-5 1-chloro-1-phenoxy-2-n-butylcyclopropane 
• 82849-48-7 1-chloro-1-phenoxy-2-cyanocyclopropane 
• 82849-45-4 1-chloro-1-phenoxy-trans-2-ethyl-3-methylcyclopropane 
• 19809-76-8 1-chloro-1-phenoxy-2,2,3,3-tetramethylcyclopropane 
• 19809-73-5 1-chloro-1-phenoxy-2,2-dimethylcyclopropane 
• 848768-04-7 3-chloro-3-(p-nitrophenoxy)diazirine 
• 350-46-9 4-Fluoronitrobenzene 

Relevant academic research and scientific papers

NOVEL HETEROCYCLIC COMPOUNDS AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS

The present invention relates to new compounds which are Heterocyclic derivatives of formula (I) wherein A, B, P, X, Y, Q, W, R1 and R2 are defined in the description. Invention compounds are useful for treating central or peripheral nervous system disorders and other disorders which are affected by the neuromodulatory effect of mGluR5 positive allosteric modulators such as cognitive decline and also to treat both positive and negative symptoms in schizophrenia.

Unprecedented chemistry of an aryloxychlorodiazirine: Generation of a dihalodiazirine and diazirinone

The reaction of p-nitrophenoxychlorodiazirine with tetrabutylammonium fluoride follows three channels: (1) ～17% of p-nitrophenoxide/fluoride exchange to chlorofluorodiazirine and p-nitrophenol, (2) ～28% of Cl/F exchange to p-nitrophenoxyfluorodiazirine, and (3) ～55% of ipso fluoride attack, affording p-nitrofluorobenzene and the previously unknown diazirinone (diazacyclopropenone). Copyright

Interaction of aryloxychlorocarbenes with acetylenedicarboxylate: Novel formation of polyfunctional butadienes and 8-oxatricyclo[3.2.1.0 2.4]oct-6-enes

The interaction of aryloxychlorocarbenes with dialkyl acetylenedicarboxylates has been examined. Thermolyses of 3-aryloxy-3- chlorodiazirines in the presence of acetylenedicarboxylate resulted in the formation of unexpected polyfunctional 1,3-butadienes and 8-oxatricyclo[3.2.1. 02.4]oct-6-enes or of 2-aryoxycarbonylmaleates dependent upon reaction conditions. This work confirmed the nucleophilicity of aryloxychlorocarbenes and underlined their synthetic potential.

Phenoxychlorocarbene, a Second Ambiphile

Phenoxychlorocarbene (PhOCCl) was generated by thermolysis (25 deg C) of 3-chloro-3-phenoxydiazirine and added to six alkenes, affording the corresponding cyclopropanes.The substrates and (relative) reactivities were tetramethylethylene (3.0), isobutene (