319432-22-9 Usage
Uses
Used in Pharmaceutical Industry:
7-IODO-PYRAZOLO[1,5-A]PYRIDINE is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to be incorporated into complex organic molecules. Its unique structure and reactivity contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 7-IODO-PYRAZOLO[1,5-A]PYRIDINE is utilized as a precursor in the creation of novel agrochemicals, leveraging its chemical properties to enhance the effectiveness of pesticides and other agricultural chemicals.
Used in Organic Synthesis:
7-IODO-PYRAZOLO[1,5-A]PYRIDINE is employed as a versatile reagent in organic synthesis, particularly for its role in facilitating certain types of organic transformations. Its presence can influence the outcome of chemical reactions, making it an indispensable component in the synthesis of a wide range of organic compounds.
Used in Chemical Research:
7-IODO-PYRAZOLO[1,5-A]PYRIDINE serves as a valuable tool in chemical research, where its unique structural features and reactivity are harnessed to explore new reaction pathways and develop innovative synthetic methods. This contributes to the advancement of chemical science and the discovery of new chemical entities.
Check Digit Verification of cas no
The CAS Registry Mumber 319432-22-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,9,4,3 and 2 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 319432-22:
(8*3)+(7*1)+(6*9)+(5*4)+(4*3)+(3*2)+(2*2)+(1*2)=129
129 % 10 = 9
So 319432-22-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H5IN2/c8-7-3-1-2-6-4-5-9-10(6)7/h1-5H
319432-22-9Relevant academic research and scientific papers
Regioselective Metalation and Functionalization of the Pyrazolo[1,5- a]pyridine Scaffold Using Mg- and Zn-TMP Bases
Balkenhohl, Moritz,Salgues, Bruno,Hirai, Takahiro,Karaghiosoff, Konstantin,Knochel, Paul
supporting information, p. 3114 - 3118 (2018/05/28)
A regioselective functionalization of the pyrazolo[1,5-a]pyridine scaffold using Mg- and Zn-TMP bases (TMP = 2,2,6,6-tetramethylpiperidyl) in the presence or absence of BF3·OEt2 is described. Also, various functionalized pyrazolo[1,5-a]pyridines bearing an ester function (and an NHBoc or ethyl group) are magnesiated and functionalized, leading to polysubstituted heterocycles. Additionally, a sulfoxide directed ortho-metalation, followed by the transition-metal-free amination of a pyrazolo[1,5-a]pyridine sulfoxide, using a magnesium amide, is reported.
Effective and variable functionalization of pyrazolo[1,5-a]pyridines involving palladium-catalyzed coupling reactions
Aboul-Fadl,Lober,Gmeiner
, p. 1727 - 1732 (2007/10/03)
Various 7-substituted pyrazolo[1,5-a]pyridines were synthesized by palladium-mediated cross-coupling reactions. Starting from the corresponding 7-iodo derivatives, incorporation of phenyl, vinyl, ethynyl, cyano, and amino was accomplished. Pyrazolo[1,5-a]