320-88-7Relevant articles and documents
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Ross et al.
, p. 4967 (1953)
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PROCESS FOR PRODUCING 2,5-BIS(TRIFLUOROMETHYL)NITROBENZENE
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Page 6, (2008/06/13)
A process to produce 2,5-bis(trifluoromethyl)nitrobenzene in a high yield from an industrially easily available material by using a substance with which the reaction operation is simple and handling is easy, with a small number of steps under moderate reaction conditions, is provided. 1,4-bis(trifluoromethyl)benzene is nitrated by means of nitric acid in a solvent comprising as an essential component an acid selected from sulfuric acid having a sulfuric acid concentration of from 91 to 100 mass% and fuming sulfuric acid having a sulfur trioxide concentration of higher than 0 mass% and at most 20 mass%.
Synthesis of trifluoromethyl aryl derivatives via difluorocarbene precursors and nitro-substituted aryl chlorides
Duan, Jian-Xing,Su, De-Bao,Wu, Jian-Ping,Chen, Qing-Yun
, p. 167 - 170 (2007/10/02)
Treatment of aryl chlorides containing electron-withdrawing proups with methyl fluorosulfonyl difluoroacetate or methyl halodifluoroacetate in the presence of potassium fluoride and copper iodide gave the corresponding trifluoromethyl derivatives in moderate to high yields.