328-92-7

Usage

Uses

Used in Organic Synthesis:
2,5-BIS(TRIFLUOROMETHYL)IODOBENZENE is used as a reagent for introducing the trifluoromethyl group into organic molecules, which is crucial for creating a range of complex compounds with potential applications in various fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2,5-BIS(TRIFLUOROMETHYL)IODOBENZENE is used as a building block for the development of new compounds with potential biological activities. Its unique properties make it a valuable component in the synthesis of drugs with novel therapeutic effects.
Used in Agrochemical Research:
Similarly, in agrochemical research, 2,5-BIS(TRIFLUOROMETHYL)IODOBENZENE is employed as a starting material for creating new compounds that may exhibit beneficial effects in agricultural applications, such as pest control and crop protection.
Used in Chemical Reactions:
2,5-BIS(TRIFLUOROMETHYL)IODOBENZENE is utilized in various substitution and coupling reactions due to its high reactivity, making it an essential tool in the synthesis of a wide array of chemical products.

Upstream product

• 328-93-8 2,5-bis(trifluoromethyl)aniline 
• 433-19-2 1,4-bis(trifluoromethyl)benzene 
• 320-88-7 1,4-Bis(trifluoromethyl)-2-nitro-benzene 

Downstream Products

• 128810-15-1 1-(3-methoxyphenyl)-4-[2,5-bis(trifluoromethyl)phenyl]-1,3-butadiyne 
• 1796930-46-5 dutasteride 
• 128971-03-9 2-[4-(2-Methoxy-phenyl)-buta-1,3-diynyl]-1,4-bis-trifluoromethyl-benzene 
• 128971-08-4 {2-[4-(2,5-Bis-trifluoromethyl-phenyl)-buta-1,3-diynyl]-phenyl}-methyl-amine 
• 128971-09-5 {3-[4-(2,5-Bis-trifluoromethyl-phenyl)-buta-1,3-diynyl]-phenyl}-methyl-amine 
• 128971-10-8 {4-[4-(2,5-Bis-trifluoromethyl-phenyl)-buta-1,3-diynyl]-phenyl}-methyl-amine 
• 128971-04-0 2-[4-(4-Methylsulfanyl-phenyl)-buta-1,3-diynyl]-1,4-bis-trifluoromethyl-benzene 
• 128810-17-3 1-(4-methoxyphenyl)-4-[2,5-bis(trifluoromethyl)phenyl]-1,3-butadiyne 
• 128971-05-1 2-[4-(2,5-Bis-trifluoromethyl-phenyl)-buta-1,3-diynyl]-phenylamine 
• 128971-07-3 4-[4-(2,5-Bis-trifluoromethyl-phenyl)-buta-1,3-diynyl]-phenylamine 
• 128971-06-2 3-[4-(2,5-Bis-trifluoromethyl-phenyl)-buta-1,3-diynyl]-phenylamine 

Relevant academic research and scientific papers

Single C?F Bond Cleavage of Trifluoromethylarenes with an ortho-Silyl Group

The transformation of a single C?F bond of trifluoromethylarenes bearing a hydrosilyl group at the ortho position was achieved. The activation of the hydrosilyl group with a trityl cation in the presence of nucleophiles allowed for selective C?F bond func

TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS

The present invention relates to tricyclic compounds of formula (I) or pharmaceutically acceptable salt thereof as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthama, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases. (I)

A scaleable synthesis of dutasteride: A selective 5α-reductase inhibitor

An improved and scaleable process for Dutasteride (1), a synthetic 4-azasteroid derivative essentially used for the treatment of prostate diseases, is described

Process for the preparation of 17beta-N-[2,5-bis(trifluoromethyl)phenyl] carbamoyl-4-aza-5-alpha-androst-1-en-3-one

The present invention relates to a process for the preparation of Dutasteride, which is chemically known as 17β-N-[2,5-bis (trifluoromethyl) phenyl] carbamoyl-4-aza-5-α-androst-1-en-3-one and can be represented by Formula (I).