3202-86-6

Usage

Uses

Used in Organic Synthesis:
(6Z)-6-(4,6-diphenyl-1,3,5-triazin-2(1H)-ylidene)cyclohexa-2,4-dien-1-one is used as a key intermediate in the synthesis of various organic materials, contributing to the development of new compounds with potential applications in different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (6Z)-6-(4,6-diphenyl-1,3,5-triazin-2(1H)-ylidene)cyclohexa-2,4-dien-1-one is utilized as a building block for the development of pharmaceutical intermediates. Its unique structure allows for the creation of novel drugs with potential therapeutic benefits.
Used in Organic Electronic Devices:
(6Z)-6-(4,6-diphenyl-1,3,5-triazin-2(1H)-ylidene)cyclohexa-2,4-dien-1-one is employed as a component in the design and fabrication of organic electronic devices, such as organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs), due to its electronic properties.
Used in Photodynamic Therapy:
In the field of cancer treatment, (6Z)-6-(4,6-diphenyl-1,3,5-triazin-2(1H)-ylidene)cyclohexa-2,4-dien-1-one has potential applications as a photosensitizer in photodynamic therapy. Its ability to absorb light and generate reactive oxygen species can be harnessed to selectively destroy cancer cells.
Used in Anti-Inflammatory and Antioxidant Applications:
(6Z)-6-(4,6-diphenyl-1,3,5-triazin-2(1H)-ylidene)cyclohexa-2,4-dien-1-one has been studied for its potential anti-inflammatory and antioxidant properties, which could be beneficial in the development of new treatments for various inflammatory and oxidative stress-related conditions.

Upstream product

• 14475-26-4 N-salicyloyl-benzamidine 
• 618-39-3 benzamidin 
• 1670-14-0 benzamidine monohydrochloride 
• 90-02-8 salicylaldehyde 
• 614-75-5 2-Hydroxyphenylacetic acid 
• 118-61-6 2-hydroxy-benzoic acid ethyl ester 

Downstream Products

• 55-21-0 benzamide 
• 65-85-0 benzoic acid 
• 108-95-2 phenol 

Relevant academic research and scientific papers

Synthesis, Spectra, and Theoretical Investigations of 1,3,5-Triazines Compounds as Ultraviolet Rays Absorber Based on Time-Dependent Density Functional Calculations and three-Dimensional Quantitative Structure-Property Relationship

A series of 1,3,5-triazines were synthesized and their UV absorption properties were tested. The computational chemistry methods were used to construct quantitative structure-property relationship (QSPR), which was used to computer aided design of new 1,3,5-triazines ultraviolet rays absorber compounds. The experimental UV absorption data are in good agreement with those predicted data using the Time-dependent density functional theory (TD-DFT) [B3LYP/6–311 + G(d,p)]. A suitable forecasting model (R > 0.8, P 0.0001) was revealed. Predictive three-dimensional quantitative structure-property relationship (3D-QSPR) model was established using multifit molecular alignment rule of Sybyl program, which conclusion is consistent with the TD-DFT calculation. The exceptional photostability mechanism of such ultraviolet rays absorber compounds was studied and confirmed as principally banked upon their ability to undergo excited-state deactivation via an ultrafast excited-state proton transfer (ESIPT). The intramolecular hydrogen bond (IMHB) of 1,3,5-triazines compounds is the basis for the excited state proton transfer, which was explored by IR spectroscopy, UV spectra, structural and energetic aspects of different conformers and frontier molecular orbitals analysis.

Transition Metal-Free sp3 C–H Functionalization of Arylacetic Acids for the Synthesis of 1,3,5-Triazines

A one-pot simple, efficient and practically viable protocol for the synthesis of substituted 1,3,5-triazines has been reported from arylacetic acids and benzamidine hydrochloride. In addition, we demonstrated first transition metal-free conversion of phenylacetic acid to benzaldehyde which on condensation with two equivalents of benzamidine hydrochloride offered 2,4,6-trisubstituted 1,3,5-triazines. This protocol is environmentally benign and economically viable which makes it feasible for gram scale synthesis.