320342-96-9

Upstream product

• 320342-75-4 methyl 2-(4-(tert-butyl)phenyl)-3-phenylpropanoate 
• 3288-99-1 4-tert-butylbenzyl cyanide 
• 100-51-6 benzyl alcohol 
• 320342-83-4 2-(4-tert-butyl-phenyl)-3-phenyl-propionic acid 
• 3549-23-3 methyl 2-(4-tert-butylphenyl)acetate 
• 100-39-0 benzyl bromide 

Downstream Products

• 320343-10-0 2-(4-tert-butyl-phenyl)-3-phenyl-propylamine 

Relevant academic research and scientific papers

Base-controlled chemoselectivity: direct coupling of alcohols and acetonitriles to synthesise α-alkylated arylacetonitriles or acetamides

We achieved chemoselective synthesis of α-alkylated arylacetonitriles and acetamides by combining Ir complex-catalysed direct coupling of alcohols and nitriles by a simple adjustment of the base. Methanol and ethanol performed well as the alkylating reagents. This method of acetonitrile alkylation provided a novel approach for carbon chain extension.