3205-18-3

Usage

Uses

Used in Pharmaceutical Synthesis:
(S)-(+)-1-Phenylethyl 3,5-dinitrobenzoate is used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. Its unique structure and reactivity contribute to the development of new drugs and medications.
Used in Chiral Building Blocks Production:
In the chemical industry, (S)-(+)-1-Phenylethyl 3,5-dinitrobenzoate serves as a crucial component in the production of chiral building blocks. These building blocks are essential for creating enantiomerically pure compounds, which are vital in the pharmaceutical, agrochemical, and fragrance industries.
Used as a Reagent in Organic Chemical Reactions:
Due to its reactivity and chiral properties, (S)-(+)-1-Phenylethyl 3,5-dinitrobenzoate is also utilized as a reagent in various organic chemical reactions. It aids in the formation of new compounds and contributes to the advancement of organic chemistry research.
Used in Optical Activity Research:
(S)-(+)-1-PHENYLETHYL 3,5-DINITROBENZOATE's ability to confer optical activity to other molecules makes it a useful tool in the study of optical activity and its applications in various fields, including the development of new materials and the understanding of molecular interactions.

InChI:InChI=1/C15H12N2O6/c1-10(11-5-3-2-4-6-11)23-15(18)12-7-13(16(19)20)9-14(8-12)17(21)22/h2-10H,1H3/t10-/m0/s1

Upstream product

• 22293-10-3 (1-diazoethyl)benzene 
• 99-34-3 3,5-dinitrobenzoic acid 
• 98-85-1 1-Phenylethanol 
• 99-33-2 3,5-dinitrobenoyl chloride 
• 1445-91-6 (S)-1-phenylethanol 
• 98-85-1 (-)-α-phenethyl alcohol 
• 1517-69-7 (R)-1-phenylethanol 
• 3205-18-3 (+/-)-sec-Phenethyl alcohol 3,5-dinitrobenzoate 
• 98-86-2 acetophenone 
• 76886-55-0 Acetophenone 2,4,6-triisopropylbenzenesulphonyl hydrazone 

Downstream Products

• 3205-33-2 (R)-sec-phenethyl-3,5-dinitrobenzoate 
• 1517-69-7 (+)-α-phenethyl alcohol 
• 4237-44-9 2-(1-phenylethyl)phenol 

Relevant academic research and scientific papers

Noncovalently Functionalized Commodity Polymers as Tailor-Made Additives for Stereoselective Crystallization

Stereoselective inhibition of the nucleation and crystal growth of one enantiomer aided by “tailor-made” polymeric additives is an efficient method to obtain enantiopure compounds. However, the conventional preparation of polymeric additives from chiral monomers are laborious and limited in structures, which impedes their rapid optimization and applicability. Herein, we report a “plug-and-play” strategy to facilitate synthesis by using commercially available achiral polymers as the platform to attach various chiral small molecules as the recognition side-chains through non-covalent interactions. A library of supramolecular polymers made up of two vinyl polymers and six small molecules were applied with seeds in the selective crystallization of seven racemates in different solvents. They showed good to excellent stereoselectivity in yielding crystals with high enantiomeric purities in conglomerates and racemic compound forming systems. This convenient, low-cost modular synthesis strategy of polymeric additives will allow for high-efficient, economical resolution of various racemates on different scales.

Recyclable mitsunobu reagents: Catalytic mitsunobu reactions with an iron catalyst and atmospheric oxygen

Aerobic recycling: A catalytic amount of a hydrazine reagent is sufficient to promote Mitsunobu reactions in the presence of triphenylphosphine, an iron catalyst, and air. The active form of the catalyst, an azo species, can be readily generated by iron-c

Chiral porphyrin dimer with a macrocyclic cavity for intercalation of aromatic guests

Chiral diporphyrin receptor 1, which has a macrocyclic cavity to sandwich aromatic guest molecules via double π-π stacking interactions, enabled the naked-eye detection of an aromatic explosive as well as chiral discrimination in NMR.

DESIGN OF STEREOSPECIFIC INHIBITORS FOR CRYSTAL DISSOLUTION

A new class of monomeric and polymeric crystal dissolution inhibitors has been prepared taking into consideration the packing arrangements and the morphologies of organic crystals.The efficiency of these inhibitors has been demonstrated by comparative morphological studies of α-glycine and by the kinetic resolution of the racemic conglomerates of his*HCl*H2O, threonine, glu*HCl, and 2,4-sec-phenetyl-3,5-dinitrobenzoate.