32111-96-9

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 63503-60-6 3-chlorophenylboronic acid 
• 3425-46-5 potassium selenocyanate 
• 108-42-9 3-chloro-aniline 

Downstream Products

• 105230-62-4 (3-chlorophenyl)(phenyl)selane 
• 1694-00-4 m-chlorophenyl methyl selenide 
• 2726-57-0 3'-Chlor-2.4-dinitro-diphenylselenid 
• 30389-55-0 1,2-bis(3-chlorophenyl)diselane 
• 141536-08-5 bis(3-chlorophenyl) selenide 
• 130956-82-0 biphenyl-4-yl-dichloro-(3-chloro-phenyl)-λ⁴-selane 
• 109014-69-9 (4-bromo-phenyl)-dichloro-(3-chloro-phenyl)-λ⁴-selane 
• 110972-84-4 dichloro-(3-chloro-phenyl)-(4-chloro-phenyl)-λ⁴-selane 
• 110054-43-8 dichloro-(3-chloro-phenyl)-m-tolyl-λ⁴-selane 
• 110062-11-8 dichloro-(3-chloro-phenyl)-p-tolyl-λ⁴-selane 
• 127764-11-8 dichloro-(3-chloro-phenyl)-phenyl-λ⁴-selane 
• 110972-83-3 (3-chloro-phenyl)-(4-chloro-phenyl)-selenide 
• 111355-47-6 biphenyl-4-yl-(3-chloro-phenyl)-selenide 
• 109014-68-8 (4-bromo-phenyl)-(3-chloro-phenyl)-selenide 

Relevant academic research and scientific papers

Metal-Free Synthesis of Aryl Selenocyanates and Selenaheterocycles with Elemental Selenium

This work reports a green method for the synthesis of aryl selenocyanates via a three-component reaction of arylboronic acids, Se powder, and trimethylsilyl cyanide (TMSCN) under metal-free and additive-free conditions. Remarkably, TMSCN acts as not only the substrate, but also the catalyst. Various selenaheterocycles can be also accessed with a catalytic amount of TMSCN.

Preparation method of arylselenocyanate compound

The invention discloses a simple and convenient method for synthesizing arylselenocyanate through reaction of three components, namely arylboronic acid, selenium powder and TMSCN under the conditionsof no metal and no additive. The preparation method has the advantages of no metal participation, no additive promotion, wide substrate range and good functional group compatibility, and provides an efficient and green way for the preparation of various aryl selenocyanates in a highly simple manner.

Synthesis of Monofluoromethyl Selenoethers of Aryl and Alkyl from Organoselenocyanate via One-Pot Reaction

The first practical and feasible approach for the monofluoromethylselenolation of aryl and alkyl halides via one-pot multistep synthesis using KSeCN and ICFH2 is described. Good yields and broad functional group compatibility were obtained. The successful preparation of monofluoromethylselenolated drug-like compounds good practicability of this method. This protocol offered a number of new monofluoromethyl selenoethers, which would accelerate the use of such compounds in the areas of life science. (Figure presented.).

The first observation of the E,Z configuration of Ar-X-N=S=N-X-Ar (X = S, Se) chains in the crystalline state

New oligomeric analogues of poly(sulfur nitride), i.e. 3-ClC 6R4-X-N=S=N-X-C6R4Cl-3 (5-8; R = H, F and X = S, Se), were synthesized and structurally characterized in the solid state by single-crystal XRD, in solution by variable-temperature NMR spectroscopy and in the gas phase with DFT/B3LYP calculations. In the crystal, compounds 5-7 display the well-known Z,Z configuration, whereas 8 (R = F, X = Se) is the first compound to display the E,Z configuration amongst twelve structurally defined Ar-X-N=S=N-X-Ar (X = S, Se) derivatives in the hydrocarbon and fluorocarbon series. Through a careful analysis of the packing schemes and the intermolecular interactions of the various compounds, an explanation of the abnormal behaviour of 8 is put forward. The unique E,Z configuration of the title compounds in the crystal is observed for Ar = 3-ClC6F 4 and X = Se - in the presence of eleven Z,Z configurations found by XRD for various Ar and X groups in the hydrocarbon and fluorocarbon series - and explained by specific intermolecular Se???Cl and F???Cl interactions. (Colour code: grey - C, green - Cl, light green - F, blue- N, orange - S, magenta - Se.)