14088-57-4

Upstream product

• 1117-96-0 Diazoethan 
• 98-88-4 benzoyl chloride 
• 3516-69-6 3-hydroxy-2-methyl-1-phenyl-2-propen-1-one 
• 93-55-0 1-phenyl-propan-1-one 
• 624-90-8 Methanesulfonyl azide 
• 322-06-5 4,4,4-trifluoro-2-methyl-1-phenyl-1,3-butanedione 
• 579-07-7 1-Phenylpropane-1,2-dione 
• 2114-00-3 2-bromo-1-phenyl-1-propanone 
• 35947-99-0 2-azido-1-phenyl-1-propanone 
• 16837-43-7 2-benzoylpropanal 

Downstream Products

• 50739-79-2 2-ethoxy-1-phenyl-propan-1-one 
• 768-03-6 Phenyl vinyl ketone 
• 19341-03-8 N-phenyl-2-phenylpropanamide 
• 106301-07-9 1-Methyl-2-phenyl-glyoxal-⁽¹⁾-tricyclohexylphosphazin 
• 6493-83-0 2-methoxy-1-phenyl-propan-1-one 
• 7624-24-0 1-methoxy-1-phenyl-acetone 
• 93-58-3 benzoic acid methyl ester 
• 31508-44-8 2-phenylpropionic acid methyl ester 
• 103230-44-0 1-phenyl-2-(triethylsilyl)propan-1-one 
• 117984-78-8 Triethyl-((E)-1-phenyl-propenyloxy)-silane 
• 66267-94-5 2-(4-Benzoyl-4-methyl-[1,3]dithietan-2-ylidene)-1-phenyl-propan-1-one 
• 118778-90-8 5-Methyl-2-[1-methyl-2-oxo-2-phenyl-eth-(E)-ylidene]-5-phenyl-[1,3]dithiolan-4-one 
• 113859-95-3 1,2,4-Trimethyl-5-phenyl-1H-pyrrole-3-carboxylic acid ethyl ester 
• 92-52-4 biphenyl 

Relevant academic research and scientific papers

Practical Application of the Aqueous 'Sulfonyl-Azide-Free' (SAFE) Diazo Transfer Protocol to Less α-C-H Acidic Ketones and Esters

The earlier described 'sulfonyl-Azide-free' ('SAFE') protocol for diazo transfer to CH-Acidic 1,3-dicarbonyl compounds (and their similarly activated congeners) has been extended to the less reactive monocarbonyl substrates, which previously required a se

Au Nanoparticle-Catalyzed Insertion of Carbenes from α-Diazocarbonyl Compounds into Hydrosilanes

Supported Au nanoparticles on TiO2 catalyze the insertion of carbenes from α-diazocabonyl compounds into hydrosilanes. It is proposed that the transformation involves two modes of catalytic activation: formation of nucleophilic Au carbenes on the surface of nanoparticle via expulsion of N2 and activation of the Si-H bond of hydrosilane on Au nanoparticle, followed by coupling of the chemisorbed species. No external ligands or additives are required, while the process is purely heterogeneous, thus allowing the recycling and reuse of the catalyst.

Site-Selective Conversion of Azido Groups at Carbonyl α-Positions to Diazo Groups in Diazido and Triazido Compounds

This paper reports on the selective conversion of alkyl azido groups at the carbonyl α-position to diazo compounds. Through β-elimination of dinitrogen, followed by hydrazone formation/decomposition, α-azidocarbonyl moieties were transformed into α-diazo carbonyl groups in one step. As these reaction conditions do not involve aryl or general alkyl azides, site-selective conversions of di- and triazides were achieved. Through this method, the successive site-selective conjugation of the triazido molecule with three different components is demonstrated.

Copper-Catalyzed Carbenoid Insertion Reactions of α-Diazoesters and α-Diazoketones into Si-H and S-H Bonds

An efficient copper-catalyzed carbenoid insertion reaction of α-diazo carbonyl compounds into Si-H and S-H bonds was developed. A wide range of α-silylesters and α-thioesters was obtained in high yields (up to 98%) from α-diazoesters using 5 mol% of a simple copper(I) salt as catalyst. Using 0.05 mol% of the same catalyst, α-diazoketones led to α-silylketones in low to good yields (up to 70%).

Cyclization Reactions of Rhodium Carbene Complexes. Effect of Composition and Oxidation State of the Metal

Treatment of o-(1,7-octadiynyl)benzoyldiazoethane with rhodium(II) octanoate in pentane resulted in a double internal/internal alkyne insertion reaction producing a labile bicyclo[4.1.0]hept-1(7)-ene derivative which readily undergoes a Diels-Alder reacti