69753-44-2

Upstream product

• 513-88-2 1,1-Dichloroacetone 
• 930-69-8 sodium thiophenolate 
• 69753-43-1 1-chloro-1-phenylthio-2-propanone 
• 108-98-5 thiophenol 
• 5042-53-5 1-(phenylsulfanyl)acetone 
• 67-64-1 acetone 
• 882-33-7 diphenyldisulfane 
• 141-97-9 ethyl acetoacetate 
• 107071-11-4 2-ethoxy-2-phenylthiopropionaldehyde 
• 2648-49-9 2-ethoxyprop-2-enal 
• 65276-67-7 N-(1-Phenylthio-2-propylidene)benzenesulfenamide 
• 38206-14-3 N-Isopropylidene-benzenesulfenamide 
• 931-59-9 benzenesulfenyl chloride 
• 1212-08-4 S-Phenyl benzenethiosulfonate 

Downstream Products

• 69753-43-1 1-chloro-1-phenylthio-2-propanone 
• 77128-60-0 3-Methyl-2-phenylsulfanyl-benzo[b]thiophene 
• 130612-85-0 α-Fluoro-α-(phenylthio)acetone 
• 5042-53-5 1-(phenylsulfanyl)acetone 
• 77128-53-1 (2R,3R)-3-Methyl-2-phenylsulfanyl-2,3-dihydro-benzo[b]thiophen-3-ol 
• 882-33-7 diphenyldisulfane 

Relevant academic research and scientific papers

Cs2CO3-promoted methylene insertion into disulfide bonds using acetone as a methylene source

An efficient halogen-free Cs2CO3-promoted methylene insertion into disulfide bonds has been achieved using acetone as a methylene source under mild conditions. This method provides a convenient and practical route to dithioacetals in up to 96% yield with good functional group compatibility.

Highly selective electrochemical fluorination of dithioacetal derivatives bearing electron-withdrawing substituents at the position α to the sulfur atom using poly(HF) salts

Anodic fluorination of dithioacetals bearing electron-withdrawing ester, acetyl, amide, and nitrile groups at their α-positions was comparatively studied using various supporting poly(HF) salts like Et3N·nHF (n = 3-5) and Et4NF·nHF (

Reactions of 2-alkoxypropenals with thiols in neutral and acid media

Addition of thiols to 2-alkoxypropenal in neutral medium at 20°C in the absence of a catalyst occurs regioselectively, following the Markownikoff pattern. The resulting 2-alkoxy-2-R-thiopropanals are capable of undergoing spontaneous isomerization to 1-al

Kinetic and thermodynamic control in the synthesis of methylglyoxal thioacetals from 2-ethoxypropenal

Under kinetically controlled conditions, the addition of organylthiols to 2-ethoxypropenal follows the Markovnikov rule to give 2-ethoxy-2-organylthiopropanals which spontaneously isomerize to 1-ethoxy- 1-organylthiopropanones in storage or in the presenc

PHOTOCHEMICAL RING CLOSURE OF α,α-BISULFENYLATED CARBONYL COMPOUNDS STEREOSELECTIVE FORMATION OF CIS-DIHYDROBENZOTHIOPHENES

Photochemistry of α,α-bisulfenylated ketone has been investigated.Irradiation of 2-phenylthiodihydrothiophen-3-one (1) in benzene gave the radical recombination products 9 (63percent) and 10 (49percent).In a polar solvent, the ionic chemistry became predominant.Brief irradiation of 1 in acetonitrile and methanol gave the cis-fused dihydrothiophene 11 as the major product in 43percent and 20percent yields, respectively.The stereoselective photocyclization was generally observed for other ketones (2-8) in acetonitrile solution (Table 1).The photoproducts were easily dehydrated by treating with boron trifluoride etherate to give the corresponding benzothiophenes in high yields.Simple α-phenylthioketones are photoinert under the same conditions.The mechanism of this novel photocyclization of bisulfenylated ketones is also discussed.

THE AdNSNE MECHANISM IN THE REACTION OF PHENOL AND BENZENETHIOL WITH α-BROMO MICHAEL ACCEPTORS IN THE K2CO3-ACETONE SYSTEM

In the reaction of α-bromo Michael acceptors with either phenol or benzenethiol formal substitution of the vinylic bromine proceeds through addition of the phenolic reagent, followed by nucleophilic substitution and β-elimination (AdNSNE mechanism) in the system K2CO3-acetone.The process is shown to be stereospecific in the case of 2a,b and 3b,c, leading to the corresponding Z isomer.The reactivity of substrates 1-4 is discussed in terms of their structural features.

Chemistry of the Sulfur-Nitrogen Bond. 15. Sulfenylation of Sulfenamide Enolate Equivalents (SEE): α-(Arylthio)sulfenimines

Studies directed toward the synthesis of α-(arylthio)sulfenimine derivatives 3 via sulfenylation of sulfenamide enolate equivalents (SEE) are described.Addition of aryl disulfides to the SEE (direct quench) afforded both the α-(arylthio)sulfenimine, 3, an

STEREOSPECIFIC PHOTOCYCLIZATION OF α-BISULFENYLATED KETO COMPOUNDS. CIS-DIHYDROBENZOTHIOPHENES.

Irradiation of α-bisulfenylated keto compounds in acetonitrile affords the cis-fused dihydrobenzothiophenes which are dehydrated to benzothiophenes in high yields.

α-CETOALDEHYDES A GROUPEMENT ALDEHYDIQUE OU CETONIQUE PROTEGE

α-Ketoaldehydes with protected ketogroup 2 or protected aldehydrogroup 3 are obtained by reaction of thiophenol or methanol with α-chloro-α-(phenylthio)aldehydes 7.