32189-00-7

Upstream product

• 3179-31-5 3-mercapto-1,2,4-triazole 
• 70-11-1 α-bromoacetophenone 
• 3179-31-5 1H-[1,2,4]triazole-3-thiol 
• 532-27-4 1-chloroacetophenone 
• 3179-31-5 2,4-dihydro-[1,2,4]triazole-3-thione 

Downstream Products

• 851538-58-4 5,6-diphenylthiazolo[3,2-b]-1,2,4-triazole 
• 1423120-78-8 5-(3-fluorophenyl)-6-phenylthiazolo[3,2-b]-1,2,4-triazole 
• 1423120-70-0 5-(3-methoxyphenyl)-6-phenyl-thiazolo[3,2-b][1,2,4]triazole 
• 1423120-71-1 5-(4-fluorophenyl)-6-phenylthiazolo[3,2-b]-1,2,4-triazole 
• 1423120-72-2 5-(4-(trifluoromethyl)phenyl)-6-phenylthiazolo[3,2-b]-1,2,4-triazole 
• 1423120-79-9 5-(naphthalen-1-yl)-6-phenylthiazolo[3,2-b]-1,2,4-triazole 
• 1423120-73-3 6-phenyl-5-p-tolylthiazolo[3,2-b]-1,2,4-triazole 
• 32189-03-0 6-Phenylthiazolo<3,2-b><1,2,4>triazole 
• 1423120-74-4 5-(4-methoxyphenyl)-6-phenylthiazolo[3,2-b]-1,2,4-triazole 
• 1423120-75-5 5-(4-tert-butylphenyl)-6-phenylthiazolo[3,2-b]-1,2,4-triazole 
• 1423120-77-7 5-(2-chlorophenyl)-6-phenylthiazolo[3,2-b]-1,2,4-triazole 

Relevant academic research and scientific papers

Synthesis of quinolines linked to triazoles through sulfur

The article summarizes the synthesis of two heterocycles linked by sulfur atom. The Friedlander reactions of 2-aminoarylketones with ketones 1, 4, and 7 have been explored, and three series of quinolines (3, 5, and 8) have been synthesized.

Synthesis of 6-Aryl-4H-imidazo[1,2-b][1,2,4]triazoles and 6-Aryl-thiazolo[3,2-b][1,2,4]triazoles

The cyclization of the derivatives of 3-aminotriazole, 2-(5-substituted 4H-1,2,4-triazol-3-ylamino)-1-arylethanones and 2-(4H-1,2,4-triazol-3-ylthio)-1-arylethanones to yield 6-aryl-4H-imidazo[1,2-b][1,2,4]triazoles and 6-aryl-thiazolo[3,2-b][1,2,4]triazoles has been described.

Cu-catalyzed direct C-H bond functionalization: A regioselective protocol to 5-aryl thiazolo[3,2-b]-1,2,4-triazoles

An efficient, regioselective C-5 arylation of thiazolo[3,2-b]-1,2,4- triazoles catalyzed by a simple copper catalyst was developed. This arylation proceeded smoothly and tolerated a variety of functional groups (44 examples). A wide range of functionalized thiazolo[3,2-b]-1,2,4-triazole derivatives were obtained in high yields (up to 99% yield). Possible catalytic cycles of the arylation were also discussed.