32189-03-0

Upstream product

• 532-27-4 1-chloroacetophenone 
• 3179-31-5 1H-[1,2,4]triazole-3-thiol 
• 70-11-1 α-bromoacetophenone 
• 32189-00-7 2-(1H-1,2,4-triazol-3-ylthio)-1-phenylethanone 
• 32189-00-7 3-Phenacylthio<1,2,4>triazole 

Downstream Products

• 851538-58-4 5,6-diphenylthiazolo[3,2-b]-1,2,4-triazole 
• 1423120-70-0 5-(3-methoxyphenyl)-6-phenyl-thiazolo[3,2-b][1,2,4]triazole 
• 1423120-71-1 5-(4-fluorophenyl)-6-phenylthiazolo[3,2-b]-1,2,4-triazole 
• 1423120-72-2 5-(4-(trifluoromethyl)phenyl)-6-phenylthiazolo[3,2-b]-1,2,4-triazole 
• 1423120-73-3 6-phenyl-5-p-tolylthiazolo[3,2-b]-1,2,4-triazole 
• 1423120-74-4 5-(4-methoxyphenyl)-6-phenylthiazolo[3,2-b]-1,2,4-triazole 
• 1423120-75-5 5-(4-tert-butylphenyl)-6-phenylthiazolo[3,2-b]-1,2,4-triazole 
• 1423120-78-8 5-(3-fluorophenyl)-6-phenylthiazolo[3,2-b]-1,2,4-triazole 
• 1574587-64-6 5-(4-bromophenyl)-6-phenylthiazolo[3,2-b][1,2,4]triazole 
• 1621514-83-7 5-D-6-phenylthiazolo[3,2-b][1,2,4]triazole 
• 1621514-69-9 6-phenyl-5-pyrimidin-5-yl-thiazolo[3,2-b][1,2,4]triazole 
• 1632154-30-3 5-(2-fluorophenyl)-6-phenylthiazolo[3,2-b][1,2,4]triazole 
• 1632154-31-4 5-(3-chlorophenyl)-6-phenylthiazolo[3,2-b][1,2,4]triazole 
• 1613053-02-3 (E)-ethyl 3-(6-phenylthiazolo[3,2-b][1,2,4]triazol-5-yl)acrylate 

Relevant academic research and scientific papers

First palladium-catalyzed direct regioselective C-5 (Het)arylation of mono- or disubstituted thiazolo[3,2-b][1,2,4]triazoles

An efficient and convenient method was developed for the formation of polysubstituted thiazolo[3,2-b][1,2,4]triazoles through C-5 (het)arylation. The direct C-H activation protocol giving access to di- and trisubstituted derivatives in excellent yields was optimized. The method is suitable for use with a wide range of (hetero)aryl bromides, and allows access to a collection of C-5,6 bis(het)aryl derivatives with full regioselectivity. The results are supported by a full description of all final compounds, and X-ray crystallographic data confirmed that the spectroscopic analyses were interpreted correctly. Copyright

Cu-catalyzed direct C-H bond functionalization: A regioselective protocol to 5-aryl thiazolo[3,2-b]-1,2,4-triazoles

An efficient, regioselective C-5 arylation of thiazolo[3,2-b]-1,2,4- triazoles catalyzed by a simple copper catalyst was developed. This arylation proceeded smoothly and tolerated a variety of functional groups (44 examples). A wide range of functionalized thiazolo[3,2-b]-1,2,4-triazole derivatives were obtained in high yields (up to 99% yield). Possible catalytic cycles of the arylation were also discussed.