32207-08-2

Upstream product

• 38043-98-0 α-Bisabolol-3-on 
• 41943-81-1 deodarone 
• 3350-78-5 3,3-Dimethylacryloyl chloride 
• 75-36-5 acetyl chloride 
• 67-64-1 acetone 
• 181809-53-0 [(E)-4-(4-Methyl-cyclohex-3-enyl)-2-oxo-pent-3-enyl]-phosphonic acid diethyl ester 
• 141-79-7 4-methyl-pent-3-en-2-one 
• 6090-09-1 (+-)-4-acetyl-1-methylcyclohexene 
• 121726-27-0 methyl-3 N-phenyl butene-3 imidothioate de methyle 
• 138-86-3 limonene. 
• 5989-27-5 D-limonene 
• 61828-50-0 4-(4-Methyl-cyclohex-3-enyl)-2-(2-methyl-propenyl)-pentane-1,2,4-triol 
• 181809-40-5 (E)-1-Iodo-4-(4-methyl-cyclohex-3-enyl)-pent-3-en-2-one 
• 181809-47-2 2-(4-Methyl-cyclohex-3-enyl)-penta-3,4-dien-2-ol 

Relevant academic research and scientific papers

One-Pot Synthesis of β,β-Disubstituted α,β-Unsaturated Carbonyl Compounds

TiCl4-promoted aldol reaction of ketones as aldol acceptors followed by elimination of the titanoxy group from the Ti-aldolates affords β,β-disubstituted α,β-unsaturated carbonyl compounds in a one-pot procedure. The use of additives, such as DMF, N,N,N′,N′-tetramethylethylenediamine, and pyridine, in the elimination step was found to be important.

Reactions with α,β-Unsaturated Nitrile Oxides. Synthetic Studies in the Terpene Field. Synthesis of Tagetones, Ocimenones, Deodarone and Atlantone

The generation and 1,3-dipolar cycloaddition of α,β-unsaturated nitrile oxides are described.Selective reductive cleavage of the isoxazoline ring was achived.Subsequent elimination of water leads to the 1,4-dien-3-one system.The formation of tetrahydro-γ-pyrones is observed.The reactions were applied to the synthesis of tagetones, ocimenones, deodarone and atlantone.

Synthese de cetones a partir de N-phenyl imidothioesters et par l'intermediaire de cetenimines

The thermal decomposition of metallated N-phenyl imidothioesters (lithium or magnesium alkylthio-enaminates generated by either deprotonation or 1,4-addition) led to ketenimines which were trapped in situ by organo-lithium or magnesium compounds to give metallated imines, readily hydrolysed into ketones.This sequence allowed the use of imidothioesters as acyl cation equivalents and also successive and regioselective > 1,3-additions of two different organometallics to an α-unsaturated imidothioester.Ar-turmerone, 2,6-dimethyl-2,7-octadien-4-one, iso-artemisia ketone, α-atlantone and other unsymmetrical ketones were synthesized by this procedure.

Regioselective Acylation of Terpene Hydrocarbons via Allyl- and Benzyltin Derivatives

Regioselective acylation of allyl- and benzylstannane derivatives derived from unsaturated terpene hydrocarbons are realized by a rhodium-catalyzed coupling with acyl halides.Mono- and sesquiterpenoid ketones which play an important role in the fragrance