322405-72-1

Basic information

• Product Name: 2-(benzyloxy)-1-(2,4,6-trihydroxyphenyl)ethanone
• Synonyms: 2-(benzyloxy)-1-(2,4,6-trihydroxyphenyl)ethanone
• CAS NO: 322405-72-1
• Molecular Weight: 274.273
• Mol File: 322405-72-1.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-(benzyloxy)-1-(2,4,6-trihydroxyphenyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzyloxy)-1-(2,4,6-trihydroxyphenyl)ethanone(322405-72-1)
• EPA Substance Registry System: 2-(benzyloxy)-1-(2,4,6-trihydroxyphenyl)ethanone(322405-72-1)

Safety Data

• Hazardous Substances Data: 322405-72-1(Hazardous Substances Data)

Upstream product

• 108-73-6 3,5-dihydroxyphenol 
• 13620-31-0 benzyloxyacetonitrile 
• 120677-47-6 1,3,5-tris(methoxymethoxy)benzene 
• 19810-31-2 Benzyloxyacetyl chloride 
• 32122-09-1 ethyl benzyloxyacetate 
• 5774-77-6 2-(benzyloxy)acetamide 
• 100-51-6 benzyl alcohol 
• 82961-70-4 2-benzyloxyacetic anhydride 

Downstream Products

• 950682-24-3 C₂₇H₄₂O₅Si₂ 
• 950682-32-3 C₅₇H₆₀O₁₂Si 
• 950682-33-4 C₅₁H₄₆O₁₂ 
• 950682-23-2 C₂₀H₃₆O₅Si₂ 
• 118169-27-0 kaempferol 3-O-(6″-O-acetyl)-β-D-glucopyranoside 
• 960365-81-5 2-(benzyloxy)-1-(2-hydroxy-4,6-bis(methoxymethoxy)phenyl)ethanone 
• 636559-68-7 C₆₃H₆₆O₇Si₃ 
• 1104336-75-5 C₆₃H₆₄O₆Si₃ 
• 1104334-73-7 C₇₀H₇₀O₆Si₃ 
• 636559-67-6 C₇₀H₇₂O₇Si₃ 
• 1616280-23-9 C₃₆H₂₄O₇ 
• 1616280-20-6 C₃₆H₂₆O₈ 
• 1616279-97-0 3-(benzyloxy)-5,7-dihydroxy-2-phenyl-4H-chromen-4-one 

Relevant articles and documents

Method for preparing icaritin intermediate

The invention provides a method for preparing an icaritin intermediate. The method includes the steps of a, enabling phloroglucinol to react with one of a 2-benzyloxy acetylation reagent and 2-benzyloxy acetonitrile to obtain 2-benzyloxy-1-(2,4,6-trihydroxyphenyl)ethanone; b. subjecting a reaction product obtained from the step a and p-methoxybenzoyl halide to Baker-Venkataraman reaction so as toobtain 3-(benzyloxy)-5,7-dihydroxy-2-(4-methoxyphenyl)-4H-benzopyran-4-one; c. subjecting the reaction product obtained in the step b to hydrogenation so as to obtain the icaritin intermediate, namely 3,5,7-trihydroxy-2-(4-methoxyphenyl)-4H-benzopyran-4-one.

Total synthesis of acetylcholinesterase inhibitor macakurzin C

A concise total synthesis of macakurzin C has been accomplished in nine steps (21% overall yield) from commercially available phloroglucinol, featuring a sequential aromatic Claisen rearrangement-cyclization.

BENZOPYRONE ESTROGEN RECEPTOR REGULATOR

The present invention provides a kind of benzopyrone compounds having a structure of formula (I) and the pharmaceutically acceptable salts or prodrugs thereof, and the pharmaceutical compositions containing such compounds, which can be used to regulate the novel estrogen receptor ER-a36, and prevent and/or treat the related diseases mediated by the ER-a36 receptor, such as cancers, etc.