322640-05-1

Basic information

• Product Name: 3,5-DIMETHOXYPHENYLMAGNESIUM BROMIDE
• Synonyms: 3,5-DIMETHOXYPHENYLMAGNESIUM BROMIDE
• CAS NO: 322640-05-1
• Molecular Formula: C₈H₉BrMgO₂
• Molecular Weight: 241.36
• Mol File: 322640-05-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,5-DIMETHOXYPHENYLMAGNESIUM BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DIMETHOXYPHENYLMAGNESIUM BROMIDE(322640-05-1)
• EPA Substance Registry System: 3,5-DIMETHOXYPHENYLMAGNESIUM BROMIDE(322640-05-1)

Safety Data

• Hazardous Substances Data: 322640-05-1(Hazardous Substances Data)

Usage

General Description

3,5-DIMETHOXYPHENYLMAGNESIUM BROMIDE is a chemical compound that is commonly used in organic synthesis as a reagent for Grignard reactions. It is a magnesium organometallic compound that contains a bromide ion and a 3,5-dimethoxyphenyl group. 3,5-DIMETHOXYPHENYLMAGNESIUM BROMIDE is known for its ability to react with a variety of organic halides, ketones, and esters to form new carbon-carbon bonds. It plays a crucial role in the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals. Overall, 3,5-DIMETHOXYPHENYLMAGNESIUM BROMIDE is a versatile and important reagent in organic chemistry.

InChI:InChI=1/C8H9O2.BrH.Mg/c1-9-7-4-3-5-8(6-7)10-2;;/h4-6H,1-2H3;1H;/q;;+1/p-1/rC8H9BrMgO2/c1-11-7-3-6(10-9)4-8(5-7)12-2/h3-5H,1-2H3

Upstream product

• 10272-07-8 3.5-dimethoxyaniline 
• 7787-70-4 copper(I) bromide 
• 7632-00-0 sodium nitrite 
• 20469-65-2 1-bromo-3,5-dimethoxybenzene 

Downstream Products

• 322640-12-0 (1R,4S)-8-(3,5-dimethoxyphenyl)menthone 
• 1381766-06-8 (R)-1-((2R,6S)-tetrahydro-6-methyl-2H-pyran-2-yl)-3-(3,5-dimethoxyphenyl)propan-2-ol 
• 1362168-22-6 9,10-bis(3,5-dimethoxyphenyl)-1,3-dimethoxyindeno[1,2,3-fg]tetracene 
• 1318240-23-1 (S)-tert-butyl 2-(3,5-dimethoxyphenylmethyl)pyrrolidine-1-carboxylate 
• 1313737-94-8 tert-butyl (2-(3,5-dimethoxyphenyl)-2-oxoethyl)carbamate 
• 1001258-87-2 (E)-[2,4-dimethoxy-6-(4-methoxystyryl)phenyl]-(3,5-dimethoxyphenyl)methanol 
• 1195055-18-5 C₂₉H₃₁NO₅ 
• 1135797-93-1 (3,5-dimethoxyphenyl)(2-phenylthiazol-4-yl)methanone 
• 1198-34-1 2-Phenylcyclopentanone 
• 88418-34-2 2-(3,5-Dimethoxyphenyl)cyclopentanone 
• 878495-92-2 (3,5-dimethoxy-phenyl)-(1,2-dimethyl-1H-benzoimidazol-5-yl)-methanol 
• 322640-61-9 (E)-9-(3-Isopropyl-2-methoxy-phenyl)-6-methyl-3-oxo-non-6-enoic acid (1S,2S,5R)-2-[1-(3,5-dimethoxy-phenyl)-1-methyl-ethyl]-5-methyl-cyclohexyl ester 
• 322640-50-6 (E)-9-(3-Isopropyl-2-methoxy-phenyl)-6-methyl-3-oxo-non-6-enoic acid (1R,2S,5R)-2-[1-(3,5-dimethoxy-phenyl)-1-methyl-ethyl]-5-methyl-cyclohexyl ester 
• 322640-35-7 (1S,2S,5R)-2-[1-(3,5-Dimethoxy-phenyl)-1-methyl-ethyl]-5-methyl-cyclohexanol 

Relevant articles and documents

Chromium(II)-Catalyzed Diastereoselective and Chemoselective Csp2-Csp3 Cross-Couplings Using Organomagnesium Reagents

A simple protocol for performing chromium-catalyzed highly diastereoselective alkylations of arylmagnesium halides with cyclohexyl iodides at ambient temperature has been developed. Furthermore, this ligand-free CrCl2 enables efficient electrophilic alkenylations of primary, secondary, and tetiary alkylmagnesium halides with readily available alkenyl acetates. Moreover, this chemoselective C-C coupling reaction with stereodefined alkenyl acetates proceeds in a stereoretentive fashion. A wide range of functional groups on alkyl iodides and alkenyl acetates are well tolerated, thus furnishing functionalized Csp2-Csp3 coupling products in good yields and high diastereoselectivity. Detailed mechanistic studies suggest that the in situ generated low-valent chromium(I) species might be the active catalyst for these Csp2-Csp3 cross-couplings.

Substituted heterocyclic compounds and uses thereof

The present invention relates to substituted heterocyclic compounds and compositions comprising a substituted heterocyclic compound. The present invention also relates to methods for preventing or treating various diseases and disorders by administering t