Magnesium bromide 3,5-dimethoxybenzen-1-ide (1/1/1)

Base Information

• Chemical Name: Magnesium bromide 3,5-dimethoxybenzen-1-ide (1/1/1)
• CAS No.: 322640-05-1
• Molecular Formula: C8H9BrMgO2
• Molecular Weight: 241.367
• DSSTox Substance ID: DTXSID90571991
• Mol file: 322640-05-1.mol

Synonyms:Magnesium bromide 3,5-dimethoxybenzen-1-ide (1/1/1);magnesium;1,3-dimethoxybenzene-5-ide;bromide;DTXSID90571991

Chemical Property of Magnesium bromide 3,5-dimethoxybenzen-1-ide (1/1/1)

Chemical Property:

• PSA: 18.46000
• LogP: 2.34960
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 239.96363
• Heavy Atom Count: 12
• Complexity: 178

Purity/Quality:

99% ^*data from raw suppliers

3,5-Dimethoxyphenylmagnesiumbromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=C[C-]=C1)OC.[Mg+2].[Br-]

Technology Process of Magnesium bromide 3,5-dimethoxybenzen-1-ide (1/1/1)

There total 2 articles about Magnesium bromide 3,5-dimethoxybenzen-1-ide (1/1/1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-bromo-3,5-dimethoxybenzene (20469-65-2) → 3,5-dimethoxyphenyl magnesium bromide (322640-05-1)

Guidance literature:

With iodine; magnesium; In tetrahydrofuran; for 3h; Heating / reflux;

Reference yield:

3.5-dimethoxyaniline (10272-07-8) + copper(I) bromide (7787-70-4) + sodium nitrite (7632-00-0) → 3,5-dimethoxyphenyl magnesium bromide (322640-05-1)

Guidance literature:

In hydrogen bromide;

Reference yield: 99.0%

C23H44O3Si2 (958241-78-6) + 3,5-dimethoxyphenyl magnesium bromide (322640-05-1) → C31H54O5Si2

Guidance literature:

C₂₃H₄₄O₃Si₂; 3,5-dimethoxyphenyl magnesium bromide; In tetrahydrofuran; at -78 ℃; for 1h; Inert atmosphere;

With ammonium chloride; In tetrahydrofuran; water; at 0 ℃;

DOI:10.1021/ol9013377

upstream raw materials:

1-bromo-3,5-dimethoxybenzene

3.5-dimethoxyaniline

copper(I) bromide

sodium nitrite

Downstream raw materials:

(1R,4S)-8-(3,5-dimethoxyphenyl)menthone

(S)-bis(3,5-dimethoxyphenyl)(pyrrolidin-2-yl)methanol

(1R,2S,5R)-2-[1-(3,5-Dimethoxy-phenyl)-1-methyl-ethyl]-5-methyl-cyclohexanol

(1S,2S,5R)-2-[1-(3,5-Dimethoxy-phenyl)-1-methyl-ethyl]-5-methyl-cyclohexanol