323195-84-2

Upstream product

• 68233-86-3 (3-Methoxy-4-methylphenyl)-methylcarbinol 
• 4685-50-1 3-methoxy-4-methylbenzyl alcohol 
• 24973-22-6 3-methoxy-4-methylbenzaldehyde 
• 7151-68-0 3-methoxy-p-toluic acid 
• 586-30-1 3-hydroxy-4-methylbenzoic acid 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 3556-81-8 1-(3-methoxy-4-methylphenyl)ethan-1-one 
• 105-36-2 ethyl bromoacetate 

Downstream Products

• 323195-87-5 (3S)-3-(3-Methoxy-4-methylphenyl)butyl iodide 
• 323195-90-0 (2E)-3-(3-Methoxy-4-methylphenyl)but-2-enal 
• 97372-52-6 (S)-(+)-Xanthorrhizol 
• 97372-51-5 (S)-(+)-Xanthorrhizol methyl ether 
• 97329-88-9 (3S)-3-(3-Methoxy-4-methylphenyl)butan-2-ol 

Relevant academic research and scientific papers

Baker's yeast-mediated enantioselective synthesis of the bisabolane sesquiterpenes (+)-curcuphenol, (+)-xanthorrhizol, (-)-curcuquinone and (+)-curcuhydroquinone

Fermenting baker's yeast converts the unsaturated aldehydes 5a-c into the saturated alcohols 6a-c, respectively. The microbial saturation of substrates adsorbed on a nonpolar resin proceeds in high chemical yields and shows complete enantioselectivity in the formation of the (S)-(+) isomers. Enantiopure 6a-c are versatile chiral building blocks for the synthesis of bisabolane sesquiterpenes. Their usefulness is shown in the preparation of (S)-(+)-curcuphenol, (S)-(+)-xanthorrhizol, (S)-(-)-curcuquinone and (S)-(+)-curcuhydroquinone. The Royal Society of Chemistry 2000.