3232-39-1Relevant articles and documents
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Bonner
, p. 4270 (1950)
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Generation of reactive oxygen species by a persulfide (BnSSH)
Chatterji, Tonika,Keerthi, Kripa,Gates, Kent S.
, p. 3921 - 3924 (2007/10/03)
Hydropersulfides (RSxSH) have been implicated as important intermediates in the cell-killing action of the anticancer natural products leinamycin and varacin. It has been suggested that persulfides can mediate the conversion of molecular oxygen to reactive oxygen species (O2 .-, H2O2, and HO.). Here, experiments with synthetic benzyl hydrodisulfide (BnSSH) provide direct evidence that persulfides readily decompose to produce reactive oxygen species under physiologically relevant conditions.
Spectroelectrochemical study of the nucleophilic substitution of diacyl disulfides by 2-nitrophenyl thiolate ions in N,N-dimethylacetamide
Ahrika,Anouti,Robert,Paris
, p. 1867 - 1874 (2007/10/03)
S-Aryl thiol esters RC(O)SAr and ArS2- ions are the end products resulting from the reactions between bis(2-nitrophenyl) disulfide Ar2S2 and thiocarboxylate ions RC(O)S- (R = Me, Ph) at 20°C. The apparent SNAr process in fact occurs in two steps as shown by UV-vis absorption spectrophotometry coupled with voltammetry: (i) formation of diacyl disulfides [RC(O)]2S2 and ArS- ions by redox exchange; (ii) subsequent nucleophilic substitution of 2-nitrophenyl thiolate ions at the carbonyl carbon of diacyl disulfides.