32322-73-9

Basic information

• Product Name: N-(SEC-BUTYL)-2-CHLOROACETAMIDE
• Synonyms: ASINEX-REAG BAS 02146892;N-(SEC-BUTYL)-2-CHLOROACETAMIDE;acetamide, 2-chloro-N-(1-methylpropyl)-;Albb-009490;N-(sec-butyl)-2-chloroacetamide(SALTDATA: FREE);2-chloro-N-sec-butylacetamide;2-chloro-N-sec-butyl-acetamide;N-butan-2-yl-2-chloroacetamide
• CAS NO: 32322-73-9
• Molecular Formula: C₆H₁₂ClNO
• Molecular Weight: 149.62
• Mol File: 32322-73-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 45.5°C
• Appearance: /
• Density: 1.0823 (rough estimate)
• Refractive Index: 1.5618 (estimate)
• CAS DataBase Reference: N-(SEC-BUTYL)-2-CHLOROACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(SEC-BUTYL)-2-CHLOROACETAMIDE(32322-73-9)
• EPA Substance Registry System: N-(SEC-BUTYL)-2-CHLOROACETAMIDE(32322-73-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 32322-73-9(Hazardous Substances Data)

Usage

General Description

N-(sec-butyl)-2-chloroacetamide is a chemical compound with the molecular formula C6H12ClNO. It is an organic compound that belongs to the class of amides, which are derived from carboxylic acids. This particular compound contains a sec-butyl group, which is a branched alkyl group, attached to a nitrogen atom, as well as a chlorine atom attached to a carbon atom in the acetamide group. It is commonly used in organic synthesis and chemical research as a building block for the preparation of various compounds. N-(sec-butyl)-2-chloroacetamide may have potential applications in pharmaceuticals, agrochemicals, and other industrial products. It is important to handle this chemical with care, as it may pose health and environmental risks if not properly managed.

Upstream product

• 33966-50-6 SEC-BUTYLAMINE 
• 7572-29-4 dichloroethyne 
• 79-04-9 chloroacetyl chloride 
• 78-81-9 isobutylamine 

Relevant articles and documents

TREATMENT OF INFECTIOUS DISEASES WITH GLUCOSE UPTAKE INHIBITORS

Provided are methods of treating infectious diseases in mammals comprising administering a compound that inhibits glucose uptake. Particular infectious diseases that may be treated include malaria, leishmaniasis, African trypanosomiasis, tuberculosis, HIV, HCMV or herpes virus. In a first aspect, the invention features a method of treating infectious diseases in a mammal, comprising administering to a mammalian subject in need thereof a therapeutically effective amount of a compound or prodrug thereof, or pharmaceutically acceptable salt or ester of said compound or prodrug, wherein the compound is an inhibitor of glucose uptake.

Complexes of selected late period lanthanide(III) cations with 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid amide (DOTAM)-alkyl ligands-A new platform for the development of paramagnetic chemical exchange saturation transfer (PARACEST) magnetic resonance imaging (MRI) contrast agents

A series of 18 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid amide (DOTAM)-alkyl derived complexes with selected late lanthanide(III) cations (Dy3+, Tb3+, and Tm3+) has been synthesized; their magnetic properties have been evaluated and compared to those derived from DOTAM. Peralkylation of cyclen with corresponding N-iodoacetyl amines was utilized as the key step in the synthesis. Chemical exchange saturation transfer (CEST) spectra of the complexes have been acquired at 37 C, revealing that Tm3+-derived DOTAM-alkyl complexes possess the most favorable properties as potential paramagnetic chemical exchange saturation transfer (PARACEST) magnetic resonance imaging (MRI) contrast agents.