3233-34-9

Usage

Uses

Used in Skincare Products:
p-Hydroxyphenyl propanoate is used as an active ingredient in skincare products for its ability to protect the skin from oxidative stress and promote overall skin health.
Used in the Food Industry:
p-Hydroxyphenyl propanoate is used as a flavoring agent and preservative in the food industry, enhancing the taste and extending the shelf life of various food products.
Used in Pharmaceutical Synthesis:
p-Hydroxyphenyl propanoate is used as a key component in the synthesis of various pharmaceuticals due to its potential therapeutic properties, contributing to the development of new treatments and medications.

InChI:InChI=1/C9H10O3/c1-2-9(11)12-8-5-3-7(10)4-6-8/h3-6,10H,2H2,1H3

Upstream product

• 123-62-6 propionic acid anhydride 
• 123-31-9 hydroquinone 
• 6628-99-5 Propionic acid 4-benzyloxy-phenyl ester 
• 7402-28-0 hydroquinone dipropionate ester 
• 79-03-8 propionyl chloride 
• 103-16-2 4-Benzyloxyphenol 
• 802294-64-0 propionic acid 

Downstream Products

• 17194-82-0 2-(4-hydroxyphenyl)acetamide 
• 147283-85-0 (4-Trifluoromethanesulfonyloxy-phenyl)-acetic acid methyl ester 
• 184416-81-7 4-[(5-trifluoromethylpyridin-2-yl)oxy]phenylacetic acid 
• 63050-16-8 4-(4-carboxy-1,2,5-trimethyl-3-pyrrylmethoxy)phenylacetic acid 

Relevant academic research and scientific papers

Kinetic studies of conjugate addition of amines to allenic and acrylic esters and their correlation with antibacterial activities against Staphylococcus aureus

Abstract: Kinetic reactivities of various allenic and acrylic esters in conjugate addition reactions with various amines were investigated. Competition experiments showed that amines reacted selectively with allenic esters, which was also confirmed by quantitative determination of the rate constants. The antibacterial activity against Staphylococcus aureus of allenic and acrylic ester derivatives were also determined. Allenic esters were found to exhibit a higher antibacterial activity than its acrylic counterparts. A correlation between the kinetic property and the antibacterial activity suggested that a conjugate addition may involve in the antibacterial mechanism of these unsaturated esters. Graphical abstract: [Figure not available: see fulltext.].

Antimicrobial activity of p-hydroxyphenyl acrylate derivatives

To estimate the antimicrobial effect of p-hydroxyphenyl acrylate (H5) derivatives on the basis of their molecular structure, the hydroxy and acryl groups of p-hydroxyphenyl acrylate were modified. The antimicrobial activity of the resulting compounds was assessed against a Gram-positive bacterium (Staphylococcus aureus), a Gram-negative bacterium (Pseudomonas aeruginosa), and fungi (Aspergillus fumigatus and Penicillium pinphilum) by the halo zone and the shake flask test. The antimicrobial activity of H5 was ascribed mainly to the acryl group. Compounds with acryl or acryloxy groups bound to the phenyl moiety were found to exhibit particularly high antimicrobial activities. The activities of phenyl acrylate and phenyl vinyl ketone were excellent as compared to aliphatic acrylates such as cyclohexyl acrylate and hexyl acrylate, indicating that the stereoelectronic effect of the phenyl group was important to the antimicrobial activity.

Isolation and production of catalytic antibodies using phage technology

Disclosed and claimed are methods for producing catalytic antibodies, including human catalytic antibodies, from bacteriophage. The methods require the cloning, selection, screening, and isolation of catalytic antibodies. Also disclosed and claimed are the products themselves, the catalytic antibodies, made from the phage technology. In addition, catalytic antibodies produced from the phage technology and useful in prodrug activation are disclosed and claimed. And finally, the invention also understands the production of catalytic antibodies to phosphonates.

Hydrolytic reactions on polyphenolic perpropanoates by porcine pancreatic lipase immobilized in microemulsion-based gels

Porcine pancreatic lipase (PPL) has been immobilized in microemulsion-based gels (MBGs). Highly selective and efficient deacylation of di/trihydric phenolic perpropanoates has been observed on incubating them with immobilized PPL. These reactions can find general utility in Synthetic Organic Chemistry.

THE EFFECT OF CARBONYL CONTAINING SUBSTITUENTS IN THE TERMINAL CHAINS ON MESOMORPHIC PROPERTIES IN AROMATIC ESTERS AND THIOESTERS, 2. ACYLOXY GROUPS ON THE PHENOLIC END

The effect of replacing an alkoxy (Y=OR') with acyloxy (Y=OCOR') group on the phenolic end of the esters: on their mesomorphic properties has been studied.These esters were prepared by esterification of 4-acyloxyphenols with the appropriate acid chloride.The phenols were synthesized by acylation of 4-benzyloxyphenol with either an aliphatic acid or acid chloride followed by catalytic hydrogenolysis of the benzyl group.A comparison of the melting and clearing temperatures of these acyloxy esters with the corresponding known alkoxy ones showed small increases in both these temperatures for the acyloxy esters.The same types of mesophases (N, SA, SC, SB) were observed in both series, but the SB was more favored when Y=OCOR'.The SC phase was found to occur in the acyloxy series at chain lengths beyond which it disappeared in the alkoxy series.Comparisons were also made with the mesomorphic properties previously reported for the correponding alkyl and α-keto esters.Some correlation was observed between increasing dipole moments of these substituents and increasing transition temperatures but not in the types of mesophases observed.Fewer mesophases were found when the alkyl chain was attached to the benzene ring through a carbon atom than through an oxygen atom.

Topical skin depigmenting composition

A stable topical skin depigmenting composition having no irritant action to the skin which comprises an active ingredient a fatty acid ester of hydroquinone of the formula: STR1 wherein R1 and R2 are the same or different, each being hydrogen or a straight or branched, saturated or unsaturated aliphatic hydrocarbon radical having 1 to 20 carbon atoms, provided that at least one of R1 and R2 is the hydrocarbon radical and one or more conventional ingredients suitable for a topical preparation. A method of depigmentation of the skin using the ester of the formula [I] is also disclosed.