3233-34-9

Basic information

• Product Name: p-Hydroxyphenyl propanoate
• Synonyms: p-Hydroxyphenyl propanoate;1-propanoate;4-hydroxyphenyl propionate
• CAS NO: 3233-34-9
• Molecular Formula: C₉H₁₀O₃
• Molecular Weight: 166.17
• Product Categories: API intermediates
• Mol File: 3233-34-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 283.066°C at 760 mmHg
• Flash Point: 122.259°C
• Appearance: /
• Density: 1.17g/cm³
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.534
• PKA: 9.36±0.15(Predicted)
• CAS DataBase Reference: p-Hydroxyphenyl propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: p-Hydroxyphenyl propanoate(3233-34-9)
• EPA Substance Registry System: p-Hydroxyphenyl propanoate(3233-34-9)

Safety Data

• Hazardous Substances Data: 3233-34-9(Hazardous Substances Data)

Usage

General Description

p-Hydroxyphenyl propanoate, also known as 4-hydroxyphenyl propionic acid, is a chemical compound commonly used in the production of pharmaceuticals, fragrances, and flavors. It is a derivative of phenylpropanoic acid and is known for its antioxidant and anti-inflammatory properties. p-Hydroxyphenyl propanoate is commonly used in skincare products due to its ability to protect the skin from oxidative stress and promote overall skin health. It is also used in the food industry as a flavoring agent and preservative. Additionally, p-Hydroxyphenyl propanoate is used in the synthesis of various pharmaceuticals due to its potential therapeutic properties, making it a versatile and valuable chemical compound in multiple industries.

InChI:InChI=1/C9H10O3/c1-2-9(11)12-8-5-3-7(10)4-6-8/h3-6,10H,2H2,1H3

Upstream product

• 123-62-6 propionic acid anhydride 
• 123-31-9 hydroquinone 
• 79-03-8 propionyl chloride 
• 802294-64-0 propionic acid 
• 103-16-2 4-Benzyloxyphenol 
• 7402-28-0 hydroquinone dipropionate ester 
• 6628-99-5 Propionic acid 4-benzyloxy-phenyl ester 

Downstream Products

• 147283-85-0 (4-Trifluoromethanesulfonyloxy-phenyl)-acetic acid methyl ester 
• 63050-16-8 4-(4-carboxy-1,2,5-trimethyl-3-pyrrylmethoxy)phenylacetic acid 
• 184416-81-7 4-[(5-trifluoromethylpyridin-2-yl)oxy]phenylacetic acid 
• 17194-82-0 2-(4-hydroxyphenyl)acetamide 

Relevant articles and documents

Kinetic studies of conjugate addition of amines to allenic and acrylic esters and their correlation with antibacterial activities against Staphylococcus aureus

Abstract: Kinetic reactivities of various allenic and acrylic esters in conjugate addition reactions with various amines were investigated. Competition experiments showed that amines reacted selectively with allenic esters, which was also confirmed by quantitative determination of the rate constants. The antibacterial activity against Staphylococcus aureus of allenic and acrylic ester derivatives were also determined. Allenic esters were found to exhibit a higher antibacterial activity than its acrylic counterparts. A correlation between the kinetic property and the antibacterial activity suggested that a conjugate addition may involve in the antibacterial mechanism of these unsaturated esters. Graphical abstract: [Figure not available: see fulltext.].

Isolation and production of catalytic antibodies using phage technology

Disclosed and claimed are methods for producing catalytic antibodies, including human catalytic antibodies, from bacteriophage. The methods require the cloning, selection, screening, and isolation of catalytic antibodies. Also disclosed and claimed are the products themselves, the catalytic antibodies, made from the phage technology. In addition, catalytic antibodies produced from the phage technology and useful in prodrug activation are disclosed and claimed. And finally, the invention also understands the production of catalytic antibodies to phosphonates.

THE EFFECT OF CARBONYL CONTAINING SUBSTITUENTS IN THE TERMINAL CHAINS ON MESOMORPHIC PROPERTIES IN AROMATIC ESTERS AND THIOESTERS, 2. ACYLOXY GROUPS ON THE PHENOLIC END

The effect of replacing an alkoxy (Y=OR') with acyloxy (Y=OCOR') group on the phenolic end of the esters: on their mesomorphic properties has been studied.These esters were prepared by esterification of 4-acyloxyphenols with the appropriate acid chloride.The phenols were synthesized by acylation of 4-benzyloxyphenol with either an aliphatic acid or acid chloride followed by catalytic hydrogenolysis of the benzyl group.A comparison of the melting and clearing temperatures of these acyloxy esters with the corresponding known alkoxy ones showed small increases in both these temperatures for the acyloxy esters.The same types of mesophases (N, SA, SC, SB) were observed in both series, but the SB was more favored when Y=OCOR'.The SC phase was found to occur in the acyloxy series at chain lengths beyond which it disappeared in the alkoxy series.Comparisons were also made with the mesomorphic properties previously reported for the correponding alkyl and α-keto esters.Some correlation was observed between increasing dipole moments of these substituents and increasing transition temperatures but not in the types of mesophases observed.Fewer mesophases were found when the alkyl chain was attached to the benzene ring through a carbon atom than through an oxygen atom.