32340-38-8

Basic information

• Product Name: 2-Propynoic acid, 3-[1,1'-biphenyl]-4-yl-
• CAS NO: 32340-38-8
• Molecular Formula: C15H10O2
• Molecular Weight: 222.243
• Mol File: 32340-38-8.mol
• Article Data: 31

Chemical Properties

• CAS DataBase Reference: 2-Propynoic acid, 3-[1,1'-biphenyl]-4-yl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propynoic acid, 3-[1,1'-biphenyl]-4-yl-(32340-38-8)
• EPA Substance Registry System: 2-Propynoic acid, 3-[1,1'-biphenyl]-4-yl-(32340-38-8)

Safety Data

• Hazardous Substances Data: 32340-38-8(Hazardous Substances Data)

Upstream product

• 124-38-9 carbon dioxide 
• 29079-00-3 4-ethynyl-1,1'-biphenyl 
• 150844-00-1 1-(biphenyl-4-yl)-2,2-dibromoethylene 
• 3218-36-8 4-Phenylbenzaldehyde 
• 1591-31-7 4-iodo-biphenyl 
• 471-25-0 Propiolic acid 
• 88241-65-0 4-phenylcinnamic acid 
• 32244-60-3 2-[Biphenyl-4-yl-(naphthalene-2-sulfonyloxy)-methylene]-malonic acid di-tert-butyl ester 
• 32244-52-3 Di-t-butyl-p-phenylbenzoylmalonat 
• 32244-79-4 2.2-Dicarboxy-1-biphenyl-4-yl-vinylnaphthalin-β-sulfonat 
• 92-66-0 4-bromo-1,1'-biphenyl 
• 5122-94-1 4-biphenylboronic acid 
• 1030-07-5 ethyl 3-([1,1'-biphenyl]-4-yl)propiolate 

Downstream Products

• 1372715-37-1 methyl 2-(2-(4-phenyl-phenyl)ethynyl)-2-phenylpent-4-enoate 
• 1363436-46-7 N-[2-(4-Biphenyl-4-ylethynyl-phenyl)-1-methyl-ethyl]acetamide 
• 941666-88-2 (E)-2-(2-([1,1′-biphenyl]-4-yl)vinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 15784-39-1 4-(phenylethynyl)-1,1'-biphenyl 
• 30166-77-9 (E)‐4‐(2-(phenylsulfonyl)vinyl)-1,1'-biphenyl 

Relevant articles and documents

Enantioselective hydroesterificative cyclization of 1,6-enynes to chiral γ-lactams bearing a quaternary carbon stereocenter

A palladium-catalyzed asymmetric hydroesterification-cyclization of 1,6-enynes with CO and alcohol was developed to efficiently prepare a variety of enantioenriched γ-lactams bearing a chiral quaternary carbon center and a carboxylic ester group. The approach featured good to high chemo-, region-, and enantioselectivities, high atom economy, and mild reaction conditions as well as broad substrate scope. The correlation between the multiple selectivities of such process and the N-substitutes of the amide linker in the 1,6-enyne substrate has been depicted by the crystallographic evidence and control experiments.

Method for synthesizing acetylenic acid by using terminal alkyne and carbon dioxide

The invention belongs to the field of organic synthesis, and particularly relates to a method for synthesizing acetylenic acid by using terminal alkyne and carbon dioxide. The method comprises the experimental steps that alkyne, alkali and a solvent are added into a reaction tube, the alkyne serves as a raw material, the alkali and the solvent provide a strong alkaline environment, CO2 is introduced into a reaction container to form a carbon dioxide atmosphere, heating and stirring reaction are carried out, after the reaction is finished, cooling is carried out to the room temperature, extraction and liquid separation are carried out, a water layer is acidified, then separation and purification are further carried out, and the acetylenic acid compound is obtained. The method is carried out under the conditions of low temperature and normal pressure, does not need to add a metal catalyst, is single in product and convenient to separate, good in substrate applicability and safe and simple to operate, and has potential industrial application prospects and good economic benefits.

Microwave-assisted fabrication of a mixed-ligand [Cu4(μ3-OH)2]-cluster-based metal–organic framework with coordinatively unsaturated metal sites for carboxylation of terminal alkynes with carbon dioxide

The development of efficient and stable metal–organic framework (MOF) catalysts with coordinatively unsaturated metal sites for modern organic synthesis is greatly important. Herein, a robust [Cu4(μ3-OH)2]-cluster-based MOF (Cu-MOF) with a mixed-ligand system was successfully fabricated by a microwave-assisted method under mild conditions. The as-prepared Cu-MOF catalyst possessing unsaturated Cu (II) sites exhibited excellent catalytic activity toward the direct carboxylation of 1-ethynylbenzene with CO2, and various propiolic acid derivatives were synthesized in moderate to good yields under optimized reaction conditions. Furthermore, the catalyst remained stable and could be easily recycled for five sequential runs without incredible decrease in catalytic efficiency.