3236-66-6

Basic information

• Product Name: 1-(2-Chloroethyl)-1H-1,2,4-triazole
• Synonyms: CHEMBRDG-BB 4010918;1H-1,2,4-TRIAZOLE, 1-(2-CHLOROETHYL)-;1-(2-CHLOROETHYL)-1H-1,2,4-TRIAZOLE;1-(2-chloroethyl)-1H-1,2,4-triazole(SALTDATA: FREE)
• CAS NO: 3236-66-6
• Molecular Formula: C₄H₆ClN₃
• Molecular Weight: 131.56
• Mol File: 3236-66-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 161-162 °C
• Boiling Point: 252.8 °C at 760 mmHg
• Flash Point: 106.7 °C
• Appearance: /
• Density: 1.34 g/cm³
• Vapor Pressure: 0.019mmHg at 25°C
• Refractive Index: 1.593
• PKA: 2.60±0.10(Predicted)
• CAS DataBase Reference: 1-(2-Chloroethyl)-1H-1,2,4-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Chloroethyl)-1H-1,2,4-triazole(3236-66-6)
• EPA Substance Registry System: 1-(2-Chloroethyl)-1H-1,2,4-triazole(3236-66-6)

Safety Data

• Hazardous Substances Data: 3236-66-6(Hazardous Substances Data)

Usage

General Description

1-(2-Chloroethyl)-1H-1,2,4-triazole is a chemical compound that belongs to the triazole class of compounds. It is a colorless to pale yellow liquid with a molecular formula of C4H5ClN4. 1-(2-Chloroethyl)-1H-1,2,4-triazole is commonly used in the production of agricultural chemicals, such as fungicides and herbicides. It is known for its ability to inhibit the growth of various types of fungi and plants. However, it is important to handle this chemical with caution as it can be toxic and harmful if not used properly. Overall, 1-(2-Chloroethyl)-1H-1,2,4-triazole is an important chemical in the agricultural industry for its fungicidal and herbicidal properties.

InChI:InChI=1/C4H6ClN3/c5-1-2-8-4-6-3-7-8/h3-4H,1-2H2

Upstream product

• 3273-14-1 1-(2-hydroxyethyl)-1H-1,2,4-triazole 
• 288-88-0 1,2,4-Triazole 
• 16670-48-7 2-chloroethyl benzenesulfonate 
• 106-93-4 ethylene dibromide 

Downstream Products

• 131727-50-9 4-(Phenyl-propionyl-amino)-1-(2-[1,2,4]triazol-1-yl-ethyl)-piperidine-4-carboxylic acid methyl ester 
• 2764-83-2 1-vinyl-1H-1,2,4-triazole 
• 467252-66-0 2-methyl-3-[2-(1H-1,2,4-triazol-1-yl)ethylsulfanyl]benzyl alcohol 
• 131727-52-1 N-[4-Methoxymethyl-1-(2-[1,2,4]triazol-1-yl-ethyl)-piperidin-4-yl]-N-phenyl-propionamide 
• 1351566-12-5 (5Z)-5-({1-[2,4-bis(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-3-[2-(1H-1,2,4-triazol-1-yl)ethyl]-1,3-thiazolidine-2,4-dione 

Relevant articles and documents

TETRAAZA-CYCLOPENTA[A]INDENYL DERIVATIVES

The present invention provides compounds of Formula (I) as M1 receptor positive allosteric modulators for the treatment of diseases mediated by the muscarinic M1 mediator.

Pyrazolopyrimidinones which inhibit type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterase (cGMP PDE5) for the treatment of sexual dysfunction

Compounds of formulae (IA) and (IB) or pharmaceutically or veterinarily acceptable salts thereof, or pharmaceutically or veterinarily acceptable solvates of either entity, wherein R1 is C1 to C3 alkyl substituted with C3 to C6 cycloalkyl, CONR5R6 or a N-linked heterocyclic group; (CH2)nHet or (CH2)nAr; R2 is C1 to C6 alkyl; R3 is C1 to C6 alkyl optionally substituted with C1 to C4 alkoxy; R4 is SO2NR7R8; R5 and R6 are each independently selected from H and C1 to C4 alkyl optionally substituted with C1 to C4 alkoxy, or, together with the nitrogen atom to which they are attached, form a 5- or 6-membered heterocyclic group; R7 and R8, together with the nitrogen atom to which they are attached, form a 4-R10-piperazinyl group; R10 is H or C1 to C4 alkyl optionally substituted with OH, C1 to C4 alkoxy or CONH2; H is an optionally substituted C-linked 5- or 6-membered heterocyclic group; Ar is optionally substituted phenyl; and n is 0 or 1; are potent and selective cGMP PDE5 inhibitors useful in the treatment of, inter alia, male erectile dysfunction and female sexual dysfunction.

Novel structures derived from 2-[[(2-pyridyl)methyl]thio]-1H-benzimidazole as anti-Helicobacter pylori agents, Part 1

2-[[(2-Pyridyl)methyl]thio]-1H-benzimidazoles (2, sulfides) exhibit antibacterial properties that are selective for Helicobacter spp., but they also have an inherent susceptibility to metabolic oxidation to furnish 2-[[(2-pyridyl)methyl]sulfinyl]-1H-benzi