3273-14-1

Usage

Uses

Used in Corrosion Inhibition:
1-(2-Hydroxyethyl)-1,2,4-triazole is used as a corrosion inhibitor for its ability to protect metal surfaces from degradation, making it valuable in industries where metal components are exposed to corrosive environments.
Used in Pharmaceutical Production:
As an intermediate in the production of pharmaceuticals, 1-(2-Hydroxyethyl)-1,2,4-triazole plays a crucial role in the synthesis of various medicinal compounds, contributing to the development of new drugs and therapies.
Used as an Antifungal Agent:
1-(2-Hydroxyethyl)-1,2,4-triazole is utilized as an antifungal agent, effective against a range of fungal infections. Its application can be found in agricultural, medical, and other industries where control of fungal growth is necessary.
Used in Organic Synthesis:
In the synthesis of other organic compounds, 1-(2-Hydroxyethyl)-1,2,4-triazole serves as a versatile building block, enabling the creation of a wide array of chemical products with diverse applications.

InChI:InChI=1/C4H7N3O/c8-2-1-7-4-5-3-6-7/h3-4,8H,1-2H2

Upstream product

• 288-88-0 1,2,4-Triazole 
• 96-49-1 [1,3]-dioxolan-2-one 
• 107-07-3 2-chloro-ethanol 
• 540-51-2 2-bromoethanol 
• 56563-01-0 ethyl 2-(1H-1,2,4-triazol-1-yl)acetate 
• 41253-21-8 sodium triazole 

Downstream Products

• 2764-83-2 1-vinyl-1H-1,2,4-triazole 
• 76321-05-6 1-(2-Vinyloxy-ethyl)-1H-[1,2,4]triazole 
• 3236-66-6 1-(2-chloroethyl)-1H-1,2,4-triazole 

Relevant academic research and scientific papers

N-terminal strategy (N1-N4) toward high performance liquid crystal materials

Liquid crystal materials have a variety of applications in many fields such as display techniques as well as photonics and optics. However, only few design principles have been disclosed on liquid crystal materials with different N-heterocycles as the terminal groups, which hinder the development of the heterocyclic liquid crystals. Here, a strategy of molecular design for N-heterocyclic liquid crystal materials is reported. On the basis of this strategy, a series of convenient N-heterocycles such as pyrrole, pyrazole, imidazole, 1,2,3-triazole, 1,2,4-triazole, 1,2,3,4-tetrazole were applied to synthesize the novel liquid crystals. Most of them have proved to exhibit good mesomorphic behaviors which make them excellent components in the mixture of the LCDs materials. The simple attachment of N-heterocyclic units to the liquid crystal molecules through a mild reaction condition will provide a good prospect for the design of N-heterocyclic liquid crystals.

TETRAAZA-CYCLOPENTA[A]INDENYL DERIVATIVES

The present invention provides compounds of Formula (I) as M1 receptor positive allosteric modulators for the treatment of diseases mediated by the muscarinic M1 mediator.

Tetraaza-cyclopenta[a]indenyl derivatives

The present invention provides compounds of Formula (I) as M1 receptor positive allosteric modulators for the treatment of diseases mediated by the muscarinic M1 mediator.

Synthesis of azolylethyl benzhydryl ethers, analogs of diphenhydramine

Alternative approaches to the preparation of azolylethyl benzhydryl ethers have been studied. It was shown that the reaction of diphenylmethyl halide with 2-(azol-1-yl)ethanol in the presence of triethylamine is the optimum way. An efficient method for the synthesis of 2-(imidazol-1-yl)ethanol using phase-transfer catalysis has been developed.

Macrolides with antibacterial activity

The invention provides new macrolides antibiotics of formula (I) with improved biological properties and improved stability formula (I): wherein R1 is hydrogen, cyano, —S(L)mR2, —S(O)(L)mR2, or —S(O)

Triazolo-pyridazine derivatives as ligands for GABA receptors

1,2,4-triazolo[4,3-b]pyridazine derivatives, possessing an optionally substituted cycloalkyl, phenyl or heteroaryl substituent as the 3-position and an amino moiety at the 6-position, are selective ligands for GABAAreceptors, in particular having high affinity for the α2 and/or α3 subunit thereof, are useful in the treatment of anxiety and convulsions.