3273-14-1

Basic information

• Product Name: 1-(2-HYDROXYETHYL)-1,2,4-TRIAZOLE
• Synonyms: 1-(2-HYDROXYETHYL)-1,2,4-TRIAZOLE;1H-1,2,4 TRIAZOLE-1-ETHANOL;CHEMBRDG-BB 4010917;2-(1H-1,2,4-triazol-1-yl)ethanol(SALTDATA: FREE);2-(1H-1,2,4-Triazol-1-yl)ethan-1-ol;2-(1H-1,2,4-Triazol-1-yl)ethanol;1-(2-Hydroxyethyl)-1H-1,2,4-triazole;2-(1,2,4-triazol-1-yl)ethanol
• CAS NO: 3273-14-1
• Molecular Formula: C₄H₇N₃O
• Molecular Weight: 113.12
• Mol File: 3273-14-1.mol
• Article Data: 6

Chemical Properties

• Melting Point: 54-56 °C(Solv: ethyl acetate (141-78-6))
• Boiling Point: 299.6 °C at 760 mmHg
• Flash Point: 135 °C
• Appearance: /
• Density: 1.32 g/cm³
• Vapor Pressure: 0.000526mmHg at 25°C
• Refractive Index: 1.601
• Storage Temp.: 2-8°C
• PKA: 13.77±0.10(Predicted)
• CAS DataBase Reference: 1-(2-HYDROXYETHYL)-1,2,4-TRIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-HYDROXYETHYL)-1,2,4-TRIAZOLE(3273-14-1)
• EPA Substance Registry System: 1-(2-HYDROXYETHYL)-1,2,4-TRIAZOLE(3273-14-1)

Safety Data

• Statements: 10
• Safety Statements: 16
• RIDADR: 1993
• HazardClass: IRRITANT
• Hazardous Substances Data: 3273-14-1(Hazardous Substances Data)

Usage

General Description

1-(2-Hydroxyethyl)-1,2,4-triazole is a chemical compound with the chemical formula C4H7N3O. It is a heterocyclic compound with a triazole ring structure. This chemical is being investigated for a variety of potential applications, including as a corrosion inhibitor, an intermediate in the production of pharmaceuticals, and as an antifungal agent. It is also used in the synthesis of other organic compounds. 1-(2-Hydroxyethyl)-1,2,4-triazole is considered to have low toxicity, but as with any chemical, proper handling and safety precautions should be followed when using it.

InChI:InChI=1/C4H7N3O/c8-2-1-7-4-5-3-6-7/h3-4,8H,1-2H2

Upstream product

• 41253-21-8 sodium triazole 
• 107-07-3 2-chloro-ethanol 
• 288-88-0 1,2,4-Triazole 
• 540-51-2 2-bromoethanol 
• 96-49-1 [1,3]-dioxolan-2-one 
• 56563-01-0 ethyl 2-(1H-1,2,4-triazol-1-yl)acetate 

Downstream Products

• 3236-66-6 1-(2-chloroethyl)-1H-1,2,4-triazole 
• 76321-05-6 1-(2-Vinyloxy-ethyl)-1H-[1,2,4]triazole 
• 2764-83-2 1-vinyl-1H-1,2,4-triazole 

Relevant articles and documents

N-terminal strategy (N1-N4) toward high performance liquid crystal materials

Liquid crystal materials have a variety of applications in many fields such as display techniques as well as photonics and optics. However, only few design principles have been disclosed on liquid crystal materials with different N-heterocycles as the terminal groups, which hinder the development of the heterocyclic liquid crystals. Here, a strategy of molecular design for N-heterocyclic liquid crystal materials is reported. On the basis of this strategy, a series of convenient N-heterocycles such as pyrrole, pyrazole, imidazole, 1,2,3-triazole, 1,2,4-triazole, 1,2,3,4-tetrazole were applied to synthesize the novel liquid crystals. Most of them have proved to exhibit good mesomorphic behaviors which make them excellent components in the mixture of the LCDs materials. The simple attachment of N-heterocyclic units to the liquid crystal molecules through a mild reaction condition will provide a good prospect for the design of N-heterocyclic liquid crystals.

Tetraaza-cyclopenta[a]indenyl derivatives

The present invention provides compounds of Formula (I) as M1 receptor positive allosteric modulators for the treatment of diseases mediated by the muscarinic M1 mediator.

Macrolides with antibacterial activity

The invention provides new macrolides antibiotics of formula (I) with improved biological properties and improved stability formula (I): wherein R1 is hydrogen, cyano, —S(L)mR2, —S(O)(L)mR2, or —S(O)