2764-83-2

Usage

Uses

1. Used in Polymer Synthesis:
1-Vinyl-1,2,4-triazole is used as a monomer in the production of poly(1-vinyl-1,2,4-triazole) and its copolymers. These polymers exhibit excellent properties such as high thermal stability, flame retardancy, and resistance to various chemicals, making them suitable for a range of applications in the plastics and coatings industries.
2. Used in Hydrogel Preparation:
1-Vinyl-1,2,4-triazole is used as an additive in the introduction of polysaccharide-based semi-degradable hydrogels. Its incorporation increases the equilibrium water content of the hydrogels, which is crucial for their performance in various applications. Additionally, it endows the hydrogels with anti-bacterial and anti-inflammatory abilities, making them suitable for use in the medical and pharmaceutical industries.
3. Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-Vinyl-1,2,4-triazole is utilized in the development of new drugs and drug delivery systems. Its unique chemical properties allow for the creation of novel drug molecules with enhanced efficacy and reduced side effects.
4. Used in Chemical Research:
1-Vinyl-1,2,4-triazole is also used as a research compound in various fields of chemistry, including organic synthesis, polymer chemistry, and materials science. Its versatile structure and reactivity make it an attractive candidate for the development of new chemical processes and materials.

InChI:InChI=1/C4H5N3/c1-2-7-4-5-3-6-7/h2-4H,1H2

Upstream product

• 288-88-0 1,2,4-Triazole 
• 108-05-4 vinyl acetate 
• 107-06-2 1,2-dichloro-ethane 
• 106-93-4 ethylene dibromide 
• 74-86-2 acetylene 
• 3273-14-1 1-(2-hydroxyethyl)-1H-1,2,4-triazole 
• 111-34-2 -butyl vinyl ether 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 2768-02-7 (vinyl)trimethoxylsilane 
• 128959-40-0 1-([1,2,4]-triazol-1-yl)-ethyl acetate 
• 3236-66-6 1-(2-chloroethyl)-1H-1,2,4-triazole 
• 593-60-2 Vinyl bromide 

Downstream Products

• 16778-70-4 1-ethyl-1H-1,2,4-triazole 

Relevant academic research and scientific papers

Water-soluble stable polymer nanocomposites with AuNPs based on the functional poly(1-vinyl-1,2,4-triazole-co-N-vinylpyrrolidone)

New water-soluble polymer nanocomposites with gold nanoparticles (AuNPs) were synthesized using functional copolymer of 1-vinyl-1,2,4-triazole with N-vinylpyrrolidone (poly(VT-co-VP)) as a stabilizing matrix. The polymer AuNPs nanocomposites were studied by transmission electron microscopy, scanning electron microscopy, ultraviolet–visible spectroscopy, Fourier transform infrared spectroscopy, X-ray diffraction, atomic absorption and thermogravimetric analysis. The gold content in nanocomposites ranged from 4.4 to 25.7%wt (the gold content depends on the ratio of poly(VT-co-VP):Au (III)). The obtained polymer nanocomposites consist of isolated gold nanoparticles with a diameter of 1–12 nm having a predominately spherical shape, which are uniformly distributed throughout the bulk of the polymer matrix. Nanocomposites contain AuNPs of various sizes, which is determined by the ability of the polymer matrix to stabilize the different metal contents. The resulting AuNPs nanocomposites are promising materials for the design of novel hydrophilic antiseptics and antimicrobial components for medical purposes.

Synthesis of 1,2,4-triazolium salt-based polymers and block copolymers by RAFT polymerization: Ion conductivity and assembled structures

Well-defined 1,2,4-triazolium-based polymers were synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization of N-vinyl-1,2,4-triazolium salts, i.e., N-vinyl-4-ethyl-1,2,4-triazolium bromide (NVETri-Br) and N-vinyl-(4-ethoxyethyl)-1,2,4-triazolium bromide (NVEtOETri-Br). Reasonable control of the polymerization of these monomers was attained using a trithiocarbonate-type chain transfer agent (CTA), producing poly(N-vinyl-1,2,4-triazolium bromide)s with controlled molecular weights (Mn,SEC > 20000) and low values (Mw/Mn 2) proceeded selectively to afford amphiphilic block copolymers composed of hydrophobic poly(NVETri-NTf2) and hydrophilic nonionic segment, poly(NVP) or poly(NVTri). The ionic conductivity of poly(NVP)33-b-poly(NVETri-NTf2)67 was 4.3 × 10-5 S/cm at 25 °C, which was remarkably higher than that of poly(NVETri-NTf2) (1.7 × 10-5 S/cm). At 90 °C, poly(NVP)-b-poly(NVETri-NTf2) exhibited high ionic conductivities of 3.1-2.3 × 10-4 S/cm under the ambient humidity conditions, depending on the comonomer composition (NVP content = 12-33%). We believe that this represents the first report on controlled synthesis of 1,2,4-triazolium-based polymers and block copolymers that exhibit high characteristic ion-conducting properties, depending on the structure of the substituent group, counter anion, comonomer structure, and composition.

Phosphine-Catalyzed Vinylation at Low Acetylene Pressure

The vinylation of various nucleophiles with acetylene at a maximum pressure of 1.5 bar is achieved by organocatalysis with easily accessible phosphines like tri-n-butylphosphine. A detailed mechanistic investigation by quantum-chemical and experimental methods supports a nucleophilic activation of acetylene by the phosphine catalyst. At 140 °C and typically 5 mol % catalyst loading, cyclic amides, oxazolidinones, ureas, unsaturated cyclic amines, and alcohols were successfully vinylated. Furthermore, the in situ generation of a vinyl phosphonium species can also be utilized in Wittig-type functionalization of aldehydes.

Hydrophobic spontaneous combustion N-hydrocarbonyl triazole dicyanoborane complex and preparation method thereof

The invention relates to a hydrophobic spontaneous combustion N-hydrocarbonyl triazole dicyanoborane complex and a preparation method thereof. The structure of the N-hydrocarbonyl triazole dicyanoborane complex is shown as a formula I. The method for prep

Synthesis of N-vinylazoles from vinyl acetate without using mercury catalysts

N-Vinyl-substituted pyrazole, 3(5)-methylpyrazole, imidazole, and 1,2,4-triazole were synthesized by addition of the corresponding azoles to vinyl acetate under conditions of phase-transfer catalysis, followed by pyrolysis of N-(1-acetoxyethyl)azoles thus formed at 350-400°C in the presence of water.

Solvent-free copper/iron co-catalyzed N-arylation reactions of nitrogen-containing heterocycles with trimethoxysilanes in air

A solvent-free copper/iron-catalyzed N-arylation of nitrogen-containing heterocycles with trimethoxysilanes method for the formation of C-N bonds has been developed. In the presence of Cu, FeCl3, TBAF, and air, a variety of nitrogen-containing heterocycles including imidazoles and triazoles were coupled with aryltrimethoxysilanes and vinyltrimethoxysilane to afford the corresponding products in moderate to excellent yields. It is noteworthy that the reaction is conducted under solvent-free and relatively low Cu/FeCl3 loadings conditions.

Synthesis of N-vinyl-1,2,3-triazole derivatives

Nitro-substituted N-vinyl-1,2,3-triazole derivatives were synthesized by the vinyl exchange reaction. The process was promoted by the catalytic system mercury(II) acetate-trifluoroacetic acid. This system is universal, and it can be used in the synthesis of vinylazoles having two, three, and four nitrogen atoms in the ring.

1,2,3-Benzothiadiazole derivatives

Novel 1,2,3-benzothiadiazole derivatives of the formula STR1 in which Het has the meanings set forth in the specification, and addition products thereof with an acid or metal salt are very effective for the control of undesired microorganisms. Novel intermediates of the formulae STR2 in which Het1 and R5 have the meanings given in the specification.

Synthesis of 1-vinyl-l,2,4-triazole

l-Vinyl-l,2,4-triazole was prepared by the reverse Favorskii's reaction.